npj Biological Physics and Mechanics

Opening threshold and kinetics of the MscL mechanosensitive channel are regulated by its periplasmic loop.

Pub Date : 2026-01-01 DOI: 10.1038/s44341-026-00048-4 Kingsley C Duru, Paul Rohde, Hooman Hafezi, Omid Bavi, Navid Bavi, Boris Martinac

A large-scale balloon model of confluent cells validates stress inference from geometry.

Pub Date : 2026-01-01 DOI: 10.1038/s44341-025-00031-5 Joseph K Hall, Yuqing Deng, Konstantinos Kontodimas, Hadi Nia, Xaralabos Varelas, Kenneth R Lutchen, Jason Bates, Béla Suki

Polarization increases nuclear stiffness in macrophages despite reduction in lamin A/C levels.

Pub Date : 2026-01-01 DOI: 10.1038/s44341-026-00038-6 Margaret A Elpers, Jacob Odell, Sarah J Henretta, Tong Shu, Yogeshwari Sanjayrao Ambekar, Hassan Saadi, Graeme F Woodworth, Warren R Zipfel, Giuliano Scarcelli, Liam J Holt, Jan Lammerding