瘤状牙基质蛋白1指导石鳖牙内氧化铁沉积

IF 45.8 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Science Pub Date : 2025-08-07 DOI:10.1126/science.adu0043

Michiko Nemoto, Koki Okada, Haruka Akamine, Yuki Odagaki, Yuka Narahara, Kenji Okoshi, Kiori Obuse, David Kisailus, Hisao Moriya, Akira Satoh

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引用次数: 0

摘要

大自然通过空间和时间上精心安排的有机矿物组合，构建了具有令人印象深刻的机械性能的多尺度矿物结构。调节矿化的一个例子是在石鳖的超矿化和超硬磁性牙齿中发现的，石鳖磨碎岩石以藻类为食。在牙齿形成的早期阶段，铁氧化物的沉积是由石壳特异性牙髓基质蛋白1 （RTMP1）控制的，该蛋白通过微绒毛运输到牙齿中。RTMP1在空间和时间上引导和增强牙齿内几质纤维的矿化，提供坚硬，坚韧和坚固的结构，使生物体能够进行重复的磨蚀事件而生存。

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Radular teeth matrix protein 1 directs iron oxide deposition in chiton teeth

Nature builds multiscale mineral structures with impressive mechanical properties through spatially and temporally orchestrated organic-mineral assembly. One example of regulated mineralization is found in hypermineralized and ultrahard magnetic teeth of chiton, which grind on rock to feed on algae. At early stages of tooth formation, iron oxide deposition is controlled using a chiton-specific radular teeth matrix protein 1 (RTMP1), which is transported into teeth through microvilli. RTMP1 spatially and temporally guides and enhances mineralization on chitinous fibers within the tooth, providing a hard, tough, and strong architecture that enables the organism to perform repetitive abrasive events to survive.

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来源期刊

Science 综合性期刊-综合性期刊

CiteScore

61.10

自引率

0.90%

发文量

审稿时长

2.1 months

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