{"title":"探索天然黄酮类薯蓣皂苷在人类疾病中的多方面潜力。","authors":"Dhirendra Singh, Randhir Singh, Inderjeet Verma","doi":"10.2174/0113816128375348250709222244","DOIUrl":null,"url":null,"abstract":"<p><p>Flavonoids are secondary metabolites that are closely related to polyphenols and have a diverse structure. These are present in the form of aglycones or glycosides in many fruits and vegetables. Diosmetin (DIO) is a bioactive flavonoid primarily found in the olive tree (Olea europaea L) and has been recognised for its diverse therapeutic potential in the management of many illnesses. In recent years, multiple pharmacological properties of DIO have been shown, including anti-inflammatory, antioxidant, antimicrobial, cardioprotective, hepatoprotective, renal protective, lung protective, retinal protective, neuroprotective and anticancer activity. Therefore, considering the pharmacological potential of DIO, the present work was designed to further explore its pharmacological actions in the treatment of various diseases.</p>","PeriodicalId":10845,"journal":{"name":"Current pharmaceutical design","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Exploring the Multifaceted Potential of Natural Flavonoid Diosmetin in Human Diseases.\",\"authors\":\"Dhirendra Singh, Randhir Singh, Inderjeet Verma\",\"doi\":\"10.2174/0113816128375348250709222244\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Flavonoids are secondary metabolites that are closely related to polyphenols and have a diverse structure. These are present in the form of aglycones or glycosides in many fruits and vegetables. Diosmetin (DIO) is a bioactive flavonoid primarily found in the olive tree (Olea europaea L) and has been recognised for its diverse therapeutic potential in the management of many illnesses. In recent years, multiple pharmacological properties of DIO have been shown, including anti-inflammatory, antioxidant, antimicrobial, cardioprotective, hepatoprotective, renal protective, lung protective, retinal protective, neuroprotective and anticancer activity. Therefore, considering the pharmacological potential of DIO, the present work was designed to further explore its pharmacological actions in the treatment of various diseases.</p>\",\"PeriodicalId\":10845,\"journal\":{\"name\":\"Current pharmaceutical design\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current pharmaceutical design\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2174/0113816128375348250709222244\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current pharmaceutical design","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0113816128375348250709222244","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Exploring the Multifaceted Potential of Natural Flavonoid Diosmetin in Human Diseases.
Flavonoids are secondary metabolites that are closely related to polyphenols and have a diverse structure. These are present in the form of aglycones or glycosides in many fruits and vegetables. Diosmetin (DIO) is a bioactive flavonoid primarily found in the olive tree (Olea europaea L) and has been recognised for its diverse therapeutic potential in the management of many illnesses. In recent years, multiple pharmacological properties of DIO have been shown, including anti-inflammatory, antioxidant, antimicrobial, cardioprotective, hepatoprotective, renal protective, lung protective, retinal protective, neuroprotective and anticancer activity. Therefore, considering the pharmacological potential of DIO, the present work was designed to further explore its pharmacological actions in the treatment of various diseases.
期刊介绍：
Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.
Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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