一氧化碳中毒后神经根病伴完整中枢神经系统影像学1例

IF 2 Q3 NEUROSCIENCES
Zhiyong Lin , Jierong Mo , Peiyi Liu , Zhiquan Li , Ran Zhan , Jun Jiang , Tianen Zhou
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引用次数: 0

摘要

目的报告并分析一例一氧化碳中毒后未累及中枢神经系统的选择性臂丛病。方法对1例25岁女性一氧化碳暴露后出现严重左上肢无力的患者进行临床检查、实验室检查、神经影像学、一系列电生理检查和功能评估。治疗包括高压氧治疗、类固醇治疗和康复治疗。结果一氧化碳中毒后,患者出现左上肢完全性麻痹,伴有选择性C5-C7运动障碍,感觉功能保留。脑MRI未见异常。电生理研究证实神经节前神经根病伴有运动神经振幅降低和感觉传导正常。超声检查显示C5-C7神经根肿胀。经过高压氧治疗、皮质类固醇和康复治疗,运动功能逐渐恢复,在120天的随访中,远端握力达到未受影响侧的86%。结论本病例表现为罕见的一氧化碳中毒,表现为孤立的臂神经根病,神经影像学显示中枢神经系统功能保留。这些发现扩大了一氧化碳神经毒性的公认范围。本病例扩展了我们对CO神经毒性的理解,超越了传统的基底神经节范式,强调了即使在中枢神经影像学正常的情况下,周围神经系统评估的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Brachial radiculopathy with intact central nervous system imaging following carbon monoxide poisoning: A case report

Objective

To report and analyze a unique case of selective brachial plexopathy following carbon monoxide poisoning without central nervous system involvement.

Methods

Clinical examination, laboratory tests, neuroimaging, serial electrophysiological studies, and functional assessments were performed on a 25-year-old female presenting with severe left upper extremity weakness after CO exposure. Treatment included hyperbaric oxygen therapy, steroid therapy, and rehabilitation.

Results

Following carbon monoxide poisoning, the patient developed complete left upper extremity paralysis with selective C5-C7 motor deficits and preserved sensory function. Brain MRI showed no abnormalities. Electrophysiological studies confirmed preganglionic radiculopathy with reduced motor nerve amplitudes and normal sensory conduction. Ultrasonography demonstrated C5-C7 nerve root swelling. Following hyperbaric oxygen therapy, corticosteroids, and rehabilitation, motor function gradually recovered with distal grip strength reaching 86% of the unaffected side at 120-day follow-up.

Conclusions

This case demonstrates an uncommon manifestation of carbon monoxide poisoning characterized by isolated brachial radiculopathy with preserved central nervous system function on neuroimaging. These findings expand the recognized spectrum of carbon monoxide neurotoxicity.

Significance

This case expands our understanding of CO neurotoxicity beyond the traditional basal ganglia paradigm, emphasizing the importance of peripheral nervous system assessment even when central neuroimaging is normal.
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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
47
审稿时长
71 days
期刊介绍: Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.
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