Cuiying Ma*, Maria Monagas, Leah Bronstein, Amy Cadwallader and Virginia Goldman*,
{"title":"膳食补充剂掺假:降低风险的实验室方法。","authors":"Cuiying Ma*, Maria Monagas, Leah Bronstein, Amy Cadwallader and Virginia Goldman*, ","doi":"10.1021/acs.jnatprod.5c00456","DOIUrl":null,"url":null,"abstract":"<p >Adulteration issues are a continuous problem facing dietary supplements (DS) manufacturers. In the past few years, major supply chain disruptions have further led to increased risk of adulteration. DS manufacturers selling products in the U.S. are required to comply with GMP, which include quality control testing to ensure that the products meet specifications for identity, purity, strength and composition, and limits on contaminants. In addition to quality control testing with compendial methods, tools to help the DS industry mitigate risks associated with adulteration include DS certification or verification programs, quality agreements with suppliers, and third-party testing.</p>","PeriodicalId":47,"journal":{"name":"Journal of Natural Products ","volume":"88 8","pages":"2029–2040"},"PeriodicalIF":3.6000,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Dietary Supplement Adulteration: Laboratory Approaches to Risk Mitigation\",\"authors\":\"Cuiying Ma*, Maria Monagas, Leah Bronstein, Amy Cadwallader and Virginia Goldman*, \",\"doi\":\"10.1021/acs.jnatprod.5c00456\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Adulteration issues are a continuous problem facing dietary supplements (DS) manufacturers. In the past few years, major supply chain disruptions have further led to increased risk of adulteration. DS manufacturers selling products in the U.S. are required to comply with GMP, which include quality control testing to ensure that the products meet specifications for identity, purity, strength and composition, and limits on contaminants. In addition to quality control testing with compendial methods, tools to help the DS industry mitigate risks associated with adulteration include DS certification or verification programs, quality agreements with suppliers, and third-party testing.</p>\",\"PeriodicalId\":47,\"journal\":{\"name\":\"Journal of Natural Products \",\"volume\":\"88 8\",\"pages\":\"2029–2040\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-07-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Natural Products \",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acs.jnatprod.5c00456\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Natural Products ","FirstCategoryId":"99","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acs.jnatprod.5c00456","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Dietary Supplement Adulteration: Laboratory Approaches to Risk Mitigation
Adulteration issues are a continuous problem facing dietary supplements (DS) manufacturers. In the past few years, major supply chain disruptions have further led to increased risk of adulteration. DS manufacturers selling products in the U.S. are required to comply with GMP, which include quality control testing to ensure that the products meet specifications for identity, purity, strength and composition, and limits on contaminants. In addition to quality control testing with compendial methods, tools to help the DS industry mitigate risks associated with adulteration include DS certification or verification programs, quality agreements with suppliers, and third-party testing.
期刊介绍:
The Journal of Natural Products invites and publishes papers that make substantial and scholarly contributions to the area of natural products research. Contributions may relate to the chemistry and/or biochemistry of naturally occurring compounds or the biology of living systems from which they are obtained.
Specifically, there may be articles that describe secondary metabolites of microorganisms, including antibiotics and mycotoxins; physiologically active compounds from terrestrial and marine plants and animals; biochemical studies, including biosynthesis and microbiological transformations; fermentation and plant tissue culture; the isolation, structure elucidation, and chemical synthesis of novel compounds from nature; and the pharmacology of compounds of natural origin.
When new compounds are reported, manuscripts describing their biological activity are much preferred.
Specifically, there may be articles that describe secondary metabolites of microorganisms, including antibiotics and mycotoxins; physiologically active compounds from terrestrial and marine plants and animals; biochemical studies, including biosynthesis and microbiological transformations; fermentation and plant tissue culture; the isolation, structure elucidation, and chemical synthesis of novel compounds from nature; and the pharmacology of compounds of natural origin.