基于改进Gabor小波变换的可解释一维卷积神经网络外显子识别。

IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
K Jayasree, Malaya Kumar Hota
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引用次数: 0

摘要

在本文中,我们提出了一种有效的一维CNN (1D-CNN)模型,该模型通过使用DSP方法(短时离散傅立叶变换和改进的Gabor小波变换)以及各种数值映射方法从DNA序列中提取特征来识别外显子。为了在不丢失特征信息的情况下保留特征信息,提出了一种排除池化层的CNN模型。实验结果表明,采用Voss-MGWT特征提取方法的1D-CNN模型在提高HMR195数据集识别精度方面优于其他讨论过的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An explainable one-dimensional convolutional neural network with modified Gabor wavelet transform for the identification of exons.

In this paper, we propose an effective one-dimensional CNN (1D-CNN) model for the identification of exons by considering the features extracted from the DNA sequences using DSP approaches (short-time discrete Fourier transform and the modified Gabor wavelet transform), along with various numerical mapping methods. To preserve the feature information without any information loss, a novel CNN model is proposed by excluding the pooling layer. The experimental outcomes reveal that the 1D-CNN model with the Voss-MGWT feature extraction method outperforms other discussed methods in improving the identification accuracy by using the HMR195 dataset.

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来源期刊
CiteScore
4.10
自引率
6.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍: The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.
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