{"title":"一种用于氯霉素检测和潜在指纹增强的双功能荧光探针","authors":"Rishabh , Manviri Rani , Uma Shanker","doi":"10.1016/j.jfca.2025.108056","DOIUrl":null,"url":null,"abstract":"<div><div>Selective and sensitive detection of chloramphenicol (CAP) in food and environmental samples was achieved through green-synthesis of nitrogen-doped carbon-quantum-dots (N-CQDs) from <em>Phyllanthus emblic</em>a. Green-technique employs a microwave-assisted-approach that is founded on green chemistry principles to produce N-CQDs with enhanced photoluminescence through N-doping. Structural characterization of samples confirmed their effective nitrogen incorporation, spherical-characterization (average-diameter: 6.49 nm), and graphitic-structure. N-CQDs exhibit robust quenching response to CAP and remarkable fluorescence-stability, with a linear-detection-range of 0.5–25 μM and detection limit of 13.1 nM. Probe's specificity is demonstrated by its resistance to interference from other antibiotics, including tetracycline and amoxicillin. Process demonstrated practical utility by achieving recovery rates of 98.13 %–105.33 % in real-world matrices such as milk, yogurt, effluent, and agricultural runoff on application. Additionally, silica nanocomposite phosphors were combined with N-CQDs for the purpose of conducting a forensic investigation. Unique luminous qualities of N-CQDs enabled the visualization of latent fingerprints in a more detailed manner, which in turn revealed distinct ridge patterns under UV illumination. This combined action demonstrates the relevance of N-CQDs in overcoming the primary obstacles in environmental monitoring, forensic science, and food safety. Additionally, this approach is reasonably priced and scalable, which suggests that it has potential for widespread application.</div></div>","PeriodicalId":15867,"journal":{"name":"Journal of Food Composition and Analysis","volume":"147 ","pages":"Article 108056"},"PeriodicalIF":4.0000,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sustainable N-CQDs from Phyllanthus emblica: A dual-function fluorescent probe for chloramphenicol detection and latent fingerprint enhancement\",\"authors\":\"Rishabh , Manviri Rani , Uma Shanker\",\"doi\":\"10.1016/j.jfca.2025.108056\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Selective and sensitive detection of chloramphenicol (CAP) in food and environmental samples was achieved through green-synthesis of nitrogen-doped carbon-quantum-dots (N-CQDs) from <em>Phyllanthus emblic</em>a. Green-technique employs a microwave-assisted-approach that is founded on green chemistry principles to produce N-CQDs with enhanced photoluminescence through N-doping. Structural characterization of samples confirmed their effective nitrogen incorporation, spherical-characterization (average-diameter: 6.49 nm), and graphitic-structure. N-CQDs exhibit robust quenching response to CAP and remarkable fluorescence-stability, with a linear-detection-range of 0.5–25 μM and detection limit of 13.1 nM. Probe's specificity is demonstrated by its resistance to interference from other antibiotics, including tetracycline and amoxicillin. Process demonstrated practical utility by achieving recovery rates of 98.13 %–105.33 % in real-world matrices such as milk, yogurt, effluent, and agricultural runoff on application. Additionally, silica nanocomposite phosphors were combined with N-CQDs for the purpose of conducting a forensic investigation. Unique luminous qualities of N-CQDs enabled the visualization of latent fingerprints in a more detailed manner, which in turn revealed distinct ridge patterns under UV illumination. This combined action demonstrates the relevance of N-CQDs in overcoming the primary obstacles in environmental monitoring, forensic science, and food safety. Additionally, this approach is reasonably priced and scalable, which suggests that it has potential for widespread application.</div></div>\",\"PeriodicalId\":15867,\"journal\":{\"name\":\"Journal of Food Composition and Analysis\",\"volume\":\"147 \",\"pages\":\"Article 108056\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2025-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Food Composition and Analysis\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0889157525008713\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Food Composition and Analysis","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0889157525008713","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Sustainable N-CQDs from Phyllanthus emblica: A dual-function fluorescent probe for chloramphenicol detection and latent fingerprint enhancement
Selective and sensitive detection of chloramphenicol (CAP) in food and environmental samples was achieved through green-synthesis of nitrogen-doped carbon-quantum-dots (N-CQDs) from Phyllanthus emblica. Green-technique employs a microwave-assisted-approach that is founded on green chemistry principles to produce N-CQDs with enhanced photoluminescence through N-doping. Structural characterization of samples confirmed their effective nitrogen incorporation, spherical-characterization (average-diameter: 6.49 nm), and graphitic-structure. N-CQDs exhibit robust quenching response to CAP and remarkable fluorescence-stability, with a linear-detection-range of 0.5–25 μM and detection limit of 13.1 nM. Probe's specificity is demonstrated by its resistance to interference from other antibiotics, including tetracycline and amoxicillin. Process demonstrated practical utility by achieving recovery rates of 98.13 %–105.33 % in real-world matrices such as milk, yogurt, effluent, and agricultural runoff on application. Additionally, silica nanocomposite phosphors were combined with N-CQDs for the purpose of conducting a forensic investigation. Unique luminous qualities of N-CQDs enabled the visualization of latent fingerprints in a more detailed manner, which in turn revealed distinct ridge patterns under UV illumination. This combined action demonstrates the relevance of N-CQDs in overcoming the primary obstacles in environmental monitoring, forensic science, and food safety. Additionally, this approach is reasonably priced and scalable, which suggests that it has potential for widespread application.
期刊介绍:
The Journal of Food Composition and Analysis publishes manuscripts on scientific aspects of data on the chemical composition of human foods, with particular emphasis on actual data on composition of foods; analytical methods; studies on the manipulation, storage, distribution and use of food composition data; and studies on the statistics, use and distribution of such data and data systems. The Journal''s basis is nutrient composition, with increasing emphasis on bioactive non-nutrient and anti-nutrient components. Papers must provide sufficient description of the food samples, analytical methods, quality control procedures and statistical treatments of the data to permit the end users of the food composition data to evaluate the appropriateness of such data in their projects.
The Journal does not publish papers on: microbiological compounds; sensory quality; aromatics/volatiles in food and wine; essential oils; organoleptic characteristics of food; physical properties; or clinical papers and pharmacology-related papers.