重新思考人脑的兴奋/抑制平衡

IF 26.7 1区医学 Q1 NEUROSCIENCES

Nature Reviews Neuroscience Pub Date : 2025-06-23 DOI:10.1038/s41583-025-00943-0

Roi Cohen Kadosh

引用次数: 0

摘要

神经兴奋(E)和抑制(I)之间的平衡决定了认知、发育和脑部疾病。脑电图和磁共振波谱可以对E/I比率进行无创量化，但产生的差异对它们在这种情况下的应用提出了挑战。解决这些差异对于推进生物标志物和基于大脑的治疗至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Rethinking excitation/inhibition balance in the human brain

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Rethinking excitation/inhibition balance in the human brain

The balance between neural excitation (E) and inhibition (I) shapes cognition, development and brain-based disorders. Electroencephalography and magnetic resonance spectroscopy allow non-invasive quantification of the E/I ratio but yield discrepancies that challenge their use in this context. Addressing these differences is essential for advancing biomarkers and brain-based therapies.

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来源期刊

Nature Reviews Neuroscience NEUROSCIENCES-

自引率

0.60%

发文量

104

期刊介绍： Nature Reviews Neuroscience is a multidisciplinary journal that covers various fields within neuroscience, aiming to offer a comprehensive understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience, facilitated by powerful experimental techniques and theoretical approaches, have made enduring neurobiological questions more accessible. Nature Reviews Neuroscience serves as a reliable and accessible resource, addressing the breadth and depth of modern neuroscience. It acts as an authoritative and engaging reference for scientists interested in all aspects of neuroscience.