Yijing Yang, Ruilin Wang, Qianchen Rui, Xiao Yan, Xun Zhu, Dingding Ye, Yang Yang, Hong Wang, Rong Chen* and Qiang Liao,
{"title":"生物应用中液滴的三维光热操作","authors":"Yijing Yang, Ruilin Wang, Qianchen Rui, Xiao Yan, Xun Zhu, Dingding Ye, Yang Yang, Hong Wang, Rong Chen* and Qiang Liao, ","doi":"10.1021/acs.analchem.4c06550","DOIUrl":null,"url":null,"abstract":"<p >3D light manipulation of water droplets at low temperatures via a local photothermal effect presents a fundamental challenge. Herein, we propose a novel light strategy for 3D manipulation of a water droplet in an immiscible oil phase using a 532 nm laser beam in which the photothermal conversion materials of carbon powders are dispersed in the oil for absorbing the 532 nm laser energy. The local photothermal effect creates temperature gradients at the oil–air and water–oil interfaces, leading to the thermocapillary flow. By controlling the laser beam position, moving speed, and irradiation mode, a water droplet can stably suspend in the oil and freely move with a complex path, presenting flexible and precise 3D manipulation of low-temperature droplets. Remarkably, the adaptability of this strategy to biological applications is demonstrated by the manipulation of diverse biodroplets while preserving their functionality. Moreover, the droplet temperature and internal flow can be well controlled, behaving like a “micro-shaker” for enhancing cell cultivation. This work represents an innovative strategy for 3D light manipulation of water droplets, which holds promise in various applications.</p>","PeriodicalId":27,"journal":{"name":"Analytical Chemistry","volume":"97 25","pages":"13010–13020"},"PeriodicalIF":6.7000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"3D Photothermal Manipulation of Droplet for Biological Applications\",\"authors\":\"Yijing Yang, Ruilin Wang, Qianchen Rui, Xiao Yan, Xun Zhu, Dingding Ye, Yang Yang, Hong Wang, Rong Chen* and Qiang Liao, \",\"doi\":\"10.1021/acs.analchem.4c06550\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >3D light manipulation of water droplets at low temperatures via a local photothermal effect presents a fundamental challenge. Herein, we propose a novel light strategy for 3D manipulation of a water droplet in an immiscible oil phase using a 532 nm laser beam in which the photothermal conversion materials of carbon powders are dispersed in the oil for absorbing the 532 nm laser energy. The local photothermal effect creates temperature gradients at the oil–air and water–oil interfaces, leading to the thermocapillary flow. By controlling the laser beam position, moving speed, and irradiation mode, a water droplet can stably suspend in the oil and freely move with a complex path, presenting flexible and precise 3D manipulation of low-temperature droplets. Remarkably, the adaptability of this strategy to biological applications is demonstrated by the manipulation of diverse biodroplets while preserving their functionality. Moreover, the droplet temperature and internal flow can be well controlled, behaving like a “micro-shaker” for enhancing cell cultivation. This work represents an innovative strategy for 3D light manipulation of water droplets, which holds promise in various applications.</p>\",\"PeriodicalId\":27,\"journal\":{\"name\":\"Analytical Chemistry\",\"volume\":\"97 25\",\"pages\":\"13010–13020\"},\"PeriodicalIF\":6.7000,\"publicationDate\":\"2025-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acs.analchem.4c06550\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acs.analchem.4c06550","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
3D Photothermal Manipulation of Droplet for Biological Applications
3D light manipulation of water droplets at low temperatures via a local photothermal effect presents a fundamental challenge. Herein, we propose a novel light strategy for 3D manipulation of a water droplet in an immiscible oil phase using a 532 nm laser beam in which the photothermal conversion materials of carbon powders are dispersed in the oil for absorbing the 532 nm laser energy. The local photothermal effect creates temperature gradients at the oil–air and water–oil interfaces, leading to the thermocapillary flow. By controlling the laser beam position, moving speed, and irradiation mode, a water droplet can stably suspend in the oil and freely move with a complex path, presenting flexible and precise 3D manipulation of low-temperature droplets. Remarkably, the adaptability of this strategy to biological applications is demonstrated by the manipulation of diverse biodroplets while preserving their functionality. Moreover, the droplet temperature and internal flow can be well controlled, behaving like a “micro-shaker” for enhancing cell cultivation. This work represents an innovative strategy for 3D light manipulation of water droplets, which holds promise in various applications.
期刊介绍:
Analytical Chemistry, a peer-reviewed research journal, focuses on disseminating new and original knowledge across all branches of analytical chemistry. Fundamental articles may explore general principles of chemical measurement science and need not directly address existing or potential analytical methodology. They can be entirely theoretical or report experimental results. Contributions may cover various phases of analytical operations, including sampling, bioanalysis, electrochemistry, mass spectrometry, microscale and nanoscale systems, environmental analysis, separations, spectroscopy, chemical reactions and selectivity, instrumentation, imaging, surface analysis, and data processing. Papers discussing known analytical methods should present a significant, original application of the method, a notable improvement, or results on an important analyte.