Ruzhe Zhang , Aamer Ali Shah , Beining Wang , Chunjie Gong
{"title":"生物工程技术生产对香豆酸的研究进展","authors":"Ruzhe Zhang , Aamer Ali Shah , Beining Wang , Chunjie Gong","doi":"10.1016/j.fbio.2025.107109","DOIUrl":null,"url":null,"abstract":"<div><div><em>p</em>-Coumaric acid is a common food additive synthesized by the plants. Due to its biological activities, <em>p-</em>coumaric acid has a wide range of applications in food, cosmetic and pharmaceutical industries. Traditionally, <em>p-</em>coumaric acid is mainly extracted from plants as well as synthesized chemically. However, the <em>p-</em>coumaric acid obtained by alkaline hydrolysis is influenced by various environmental factors. On the other hand, the chemical synthesis requires high energy and ultimately leads to environmental pollution. The bio-based production of <em>p-</em>coumaric acid has gained more attention after the development of bioengineering strategies. Biosynthesis of <em>p-</em>coumaric acid exhibited advantages of low cost, high efficiency, and suitable to large-scale production in industry. This review comprehensively summarized the bioengineering technologies for the production of <em>p</em>-coumaric acid, such as enzyme engineering, metabolic pathway reconstruction, and tolerance improvement. At last, the economic-techno feasibility of bioengineering technologies to <em>p</em>-coumaric acid production is analyzed.</div></div>","PeriodicalId":12409,"journal":{"name":"Food Bioscience","volume":"71 ","pages":"Article 107109"},"PeriodicalIF":4.8000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Current progress of p-coumaric acid production using bioengineering technologies\",\"authors\":\"Ruzhe Zhang , Aamer Ali Shah , Beining Wang , Chunjie Gong\",\"doi\":\"10.1016/j.fbio.2025.107109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>p</em>-Coumaric acid is a common food additive synthesized by the plants. Due to its biological activities, <em>p-</em>coumaric acid has a wide range of applications in food, cosmetic and pharmaceutical industries. Traditionally, <em>p-</em>coumaric acid is mainly extracted from plants as well as synthesized chemically. However, the <em>p-</em>coumaric acid obtained by alkaline hydrolysis is influenced by various environmental factors. On the other hand, the chemical synthesis requires high energy and ultimately leads to environmental pollution. The bio-based production of <em>p-</em>coumaric acid has gained more attention after the development of bioengineering strategies. Biosynthesis of <em>p-</em>coumaric acid exhibited advantages of low cost, high efficiency, and suitable to large-scale production in industry. This review comprehensively summarized the bioengineering technologies for the production of <em>p</em>-coumaric acid, such as enzyme engineering, metabolic pathway reconstruction, and tolerance improvement. At last, the economic-techno feasibility of bioengineering technologies to <em>p</em>-coumaric acid production is analyzed.</div></div>\",\"PeriodicalId\":12409,\"journal\":{\"name\":\"Food Bioscience\",\"volume\":\"71 \",\"pages\":\"Article 107109\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2025-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Bioscience\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212429225012866\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Bioscience","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212429225012866","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Current progress of p-coumaric acid production using bioengineering technologies
p-Coumaric acid is a common food additive synthesized by the plants. Due to its biological activities, p-coumaric acid has a wide range of applications in food, cosmetic and pharmaceutical industries. Traditionally, p-coumaric acid is mainly extracted from plants as well as synthesized chemically. However, the p-coumaric acid obtained by alkaline hydrolysis is influenced by various environmental factors. On the other hand, the chemical synthesis requires high energy and ultimately leads to environmental pollution. The bio-based production of p-coumaric acid has gained more attention after the development of bioengineering strategies. Biosynthesis of p-coumaric acid exhibited advantages of low cost, high efficiency, and suitable to large-scale production in industry. This review comprehensively summarized the bioengineering technologies for the production of p-coumaric acid, such as enzyme engineering, metabolic pathway reconstruction, and tolerance improvement. At last, the economic-techno feasibility of bioengineering technologies to p-coumaric acid production is analyzed.
Food BioscienceBiochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
6.40
自引率
5.80%
发文量
671
审稿时长
27 days
期刊介绍:
Food Bioscience is a peer-reviewed journal that aims to provide a forum for recent developments in the field of bio-related food research. The journal focuses on both fundamental and applied research worldwide, with special attention to ethnic and cultural aspects of food bioresearch.