在细针穿刺活检（FNAB）甲状腺样本中实现多基因分子面板：一个令人信服的诊断和预后模型。

IF 1.1 4区医学 Q4 CELL BIOLOGY

Cytopathology Pub Date : 2025-06-18 DOI:10.1111/cyt.70004

Angeliki Margoni, Kostas A. Papavassiliou, Athanasios G. Papavassiliou

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引用次数: 0

摘要

多基因面板在FNAB甲状腺样本中的应用提供了一种以患者为导向的诊断和预后模型。一些基因突变和分子标记与甲状腺癌的组织学亚型相关，揭示了分子技术在靶向治疗中的潜在作用。FNAB和多基因检测的结合向临床医生介绍了精确肿瘤学的好处。

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Implementation of a Multi-Gene Molecular Panel at Fine Needle Aspiration Biopsy (FNAB) Thyroid Samples: A Compelling Diagnostic and Prognostic Model

Application of a multi-gene panel in FNAB thyroid samples provides a patient-directed diagnostic and prognostic model. Several genetic mutations and molecular markers are correlated with histological subtypes of thyroid cancer, revealing the potential role of molecular techniques in targeted therapy. The combination of FNAB and multi-gene tests introduces clinicians to the benefits of precision oncology.

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来源期刊

Cytopathology 生物-病理学

CiteScore

2.30

自引率

15.40%

发文量

107

审稿时长

6-12 weeks

期刊介绍： The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.