基于决策树和进化算法的人工智能模型在初级保健环境中评估脂肪变性肝病的效用。

IF 1.9 4区 医学 Q2 BIOLOGY
A C Goulart, A P Alencar, G Tunes, L L T Bianchi, M H Miname, C M Padilha, J M S Pescuma, A L C C Rodrigues, B B Henares, M S de Almeida, T A O Machado, D H Syllos, Y P Wang, M Rienzo
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引用次数: 0

摘要

人们提出了许多将脂肪变性肝病(SLD)与代谢疾病分类的方法。因此,使用决策树来验证与sld相关的变量。我们测试了实际分类的建议成分(代谢功能障碍相关脂肪变性肝病,MASLD)是否也存在于青壮年成年人中。在一项涉及6839名成人(中位年龄:46岁,男性69.5%)的横断面研究中,我们创建了一个决策树来确定与SLD相关的潜在临床和实验室变量。计算男女的比值比(OR)和各自的95%置信区间(95% ci)。SLD发生率为26.6%(男性23%)。在女性中发现了与SLD相关的更多变量和更高的or: 1类(体重指数(BMI)≥29 kg/m2,年龄)
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The utility of an artificial intelligence model based on decision tree and evolution algorithm to evaluate steatotic liver disease in a primary care setting.

The utility of an artificial intelligence model based on decision tree and evolution algorithm to evaluate steatotic liver disease in a primary care setting.

The utility of an artificial intelligence model based on decision tree and evolution algorithm to evaluate steatotic liver disease in a primary care setting.

Many ways of classifying steatotic liver disease (SLD) with metabolic conditions have been proposed. Thus, SLD-related variables were verified using a decision tree. We tested if the suggested components of the actual classification (metabolic dysfunction-associated steatotic liver disease, MASLD) are also present in young and middle-aged adults. In a cross-sectional study involving 6,839 adults (median age: 46 years, 69.5% men) in a primary care setting, a decision tree was created to determine potential clinical and laboratory variables related to SLD. The odds ratio (OR) with a respective 95% confidence interval (95%CI) was calculated for both sexes. SLD frequency was 26.6% (23% in men). More variables and with higher ORs for the association with SLD were identified in women: category 1 (body mass index (BMI) ≥29 kg/m2, age <51 years, high-sensitivity C-reactive protein (hs-CRP) ≥0.195 mg/dL): OR=10.9, 95%CI: 4.40-26.6; category 2 (BMI <9 kg/m2, metabolic syndrome (MS), age ≥50 years, neck circumference (NC) ≥36 cm): OR=8.1, 95%CI: 2.2-29.9; and category 3 (BMI ≥29 kg/m2, age <51 y-old, dyslipidemia, high-density lipoprotein cholesterol (HDL-c) <42 mg/dL): OR=4.7, 95%CI: 2.20-10.7. For men: category 1 (waist circumference (WC) ≥101 cm, alanine aminotransferase (ALT) <28 mg/dL, glycated hemoglobin (HbA1c) ≥5.7%): OR=4.7, 95%CI: 2.8-7.9; and category 2 (WC ≥101 cm, ALT ≥28 mg/dL): OR=3.2, 95%CI: 2.5-4.0). The decision tree identified more variables related to SLD, particularly in women, such as age of more than 50 years, elevated hs-CRP, and NC≥36 cm than variables related to MASLD.

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来源期刊
CiteScore
4.00
自引率
0.00%
发文量
129
审稿时长
2 months
期刊介绍: The Brazilian Journal of Medical and Biological Research, founded by Michel Jamra, is edited and published monthly by the Associação Brasileira de Divulgação Científica (ABDC), a federation of Brazilian scientific societies: - Sociedade Brasileira de Biofísica (SBBf) - Sociedade Brasileira de Farmacologia e Terapêutica Experimental (SBFTE) - Sociedade Brasileira de Fisiologia (SBFis) - Sociedade Brasileira de Imunologia (SBI) - Sociedade Brasileira de Investigação Clínica (SBIC) - Sociedade Brasileira de Neurociências e Comportamento (SBNeC).
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