健康跨度的定义:系统回顾。

IF 12.4 1区 医学 Q1 CELL BIOLOGY
Siti Masfiah , Alfarid Kurnialandi , Johannes Jacobus Meij , Andrea Britta Maier
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引用次数: 0

摘要

“健康跨度”一词已广泛用于学术文献、技术报告和小册子,但目前尚不清楚是否正在使用与“健康跨度”相同的定义和操作方法。本系统综述(注册号CRD42023404872)的目的是总结健康跨度的定义及其在PubMed、Embase、Web of Science和Scopus四个数据库中的操作化搜索。在14,551条记录中,207条记录符合纳入标准,187篇文章给出了健康跨度的定义。其中113个定义被认为是初级定义,它们引用作者的定义而不引用其他定义。健康跨度的定义差别很大,描述了没有各种疾病和/或残疾,并通过衡量慢性病、残疾或工作能力限制的发生来实施。两种定义包括主观衡量标准,如生活质量。总之,健康跨度的定义及其操作没有标准化,妨碍了数据的比较。迫切需要就健康跨度的定义和实施达成共识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Definitions of healthspan: A systematic review
The term healthspan has been widely used in academic literature, technical reports and brochures, however, it is unclear if the same definitions and operationalizations for healthspan are being used. The objective of the systematic review (registration number CRD42023404872) was to summarize definitions of healthspan and their operationalization searching using four databases: PubMed, Embase, Web of Science, and Scopus. Out of 14,551 records, 207 records met the inclusion criteria and 187 articles gave a definition of healthspan. Of these, 113 definitions were considered primary definitions, which refer to an authors' definition without referencing other definitions. Healthspan definitions varied widely, describing the absence of various disease and or disability and were operationalized by measuring the onset of chronic diseases, disability or performance limitations. Two definitions included subjective measures, such as quality of life. In conclusion, definitions of healthspan and their operationalization are not standardized, hampering comparisons of data. A consensus on the definition and operationalization of healthspan is urgently needed.
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来源期刊
Ageing Research Reviews
Ageing Research Reviews 医学-老年医学
CiteScore
19.80
自引率
2.30%
发文量
216
审稿时长
55 days
期刊介绍: With the rise in average human life expectancy, the impact of ageing and age-related diseases on our society has become increasingly significant. Ageing research is now a focal point for numerous laboratories, encompassing leaders in genetics, molecular and cellular biology, biochemistry, and behavior. Ageing Research Reviews (ARR) serves as a cornerstone in this field, addressing emerging trends. ARR aims to fill a substantial gap by providing critical reviews and viewpoints on evolving discoveries concerning the mechanisms of ageing and age-related diseases. The rapid progress in understanding the mechanisms controlling cellular proliferation, differentiation, and survival is unveiling new insights into the regulation of ageing. From telomerase to stem cells, and from energy to oxyradical metabolism, we are witnessing an exciting era in the multidisciplinary field of ageing research. The journal explores the cellular and molecular foundations of interventions that extend lifespan, such as caloric restriction. It identifies the underpinnings of manipulations that extend lifespan, shedding light on novel approaches for preventing age-related diseases. ARR publishes articles on focused topics selected from the expansive field of ageing research, with a particular emphasis on the cellular and molecular mechanisms of the aging process. This includes age-related diseases like cancer, cardiovascular disease, diabetes, and neurodegenerative disorders. The journal also covers applications of basic ageing research to lifespan extension and disease prevention, offering a comprehensive platform for advancing our understanding of this critical field.
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