Ageing Research Reviews

With the rise in average human life expectancy, the impact of ageing and age-related diseases on our society has become increasingly significant. Ageing research is now a focal point for numerous laboratories, encompassing leaders in genetics, molecular and cellular biology, biochemistry, and behavior. Ageing Research Reviews (ARR) serves as a cornerstone in this field, addressing emerging trends. ARR aims to fill a substantial gap by providing critical reviews and viewpoints on evolving discoveries concerning the mechanisms of ageing and age-related diseases. The rapid progress in understanding the mechanisms controlling cellular proliferation, differentiation, and survival is unveiling new insights into the regulation of ageing. From telomerase to stem cells, and from energy to oxyradical metabolism, we are witnessing an exciting era in the multidisciplinary field of ageing research. The journal explores the cellular and molecular foundations of interventions that extend lifespan, such as caloric restriction. It identifies the underpinnings of manipulations that extend lifespan, shedding light on novel approaches for preventing age-related diseases. ARR publishes articles on focused topics selected from the expansive field of ageing research, with a particular emphasis on the cellular and molecular mechanisms of the aging process. This includes age-related diseases like cancer, cardiovascular disease, diabetes, and neurodegenerative disorders. The journal also covers applications of basic ageing research to lifespan extension and disease prevention, offering a comprehensive platform for advancing our understanding of this critical field.

随着人类寿命的延长，老龄化和与年龄相关的疾病对社会的影响日益显著。 许多实验室现在将研究重点放在了老龄化领域，包括遗传学、分子生物学、细胞生物学、生物化学和行为学等领域的领先研究者。《Ageing Research Reviews》（ARR）是这一领域的重要期刊，旨在概述和评述新兴趋势。 ARR 通过对衰老和年龄相关疾病机制的不断发现提供批判性评论和观点，填补了重要的知识空白。对于控制细胞增殖、分化和存活机制的快速了解正在揭示出新的衰老调节机制。从端粒酶到干细胞，再到能量代谢和氧自由基，我们正在经历衰老研究跨学科领域的一个令人兴奋的时代。 Ageing Research Reviews探讨了延长寿命的细胞和分子基础，例如热量限制。 它阐明了延长寿命的操作机制，揭示了预防与年龄相关的疾病的新途径。该期刊发表的文章涵盖了衰老研究领域的广泛主题，特别强调了衰老过程的细胞和分子机制。这些主题包括癌症、心血管疾病、糖尿病和神经退行性疾病等年龄相关疾病。 该期刊还涵盖了基础衰老研究在延长寿命和预防疾病方面的应用，为提高读者对这一关键领域的理解提供了一个全面的平台。