Lauren N Irwin Harper, Julia C Nahman, Luis Ahumada, Mohamed Rehman, Sarah Irani, P Patrick Mularoni, Danielle M Ransom
{"title":"青少年从运动相关脑震荡中恢复的神经认知评估：一项利用美国国立卫生研究院工具箱认知电池的前瞻性队列试点研究。","authors":"Lauren N Irwin Harper, Julia C Nahman, Luis Ahumada, Mohamed Rehman, Sarah Irani, P Patrick Mularoni, Danielle M Ransom","doi":"10.1080/21622965.2025.2507326","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study explored NIHTB-CB's utility in assessing cognitive recovery in adolescents with SRC. We hypothesized the NIHTB-CB is sensitive to detecting weaknesses in fluid, but not crystalized, cognition, and adolescents recovering from SRC exhibit greater weaknesses than orthopedically injured (OI) adolescents.</p><p><strong>Method: </strong>Thirty-six participants diagnosed with SRC or OI were enrolled in a pilot study and completed the NIHTB-CB at the time of enrollment and 4-6 weeks post-injury clearance. A total of 14 participants were excluded from analyses due to attrition (<i>n</i> = 4) and PVT failure (<i>n</i> = 10), with 22 participants included in final analyses (SRC <i>n</i> = 10; OI <i>n =</i> 12).</p><p><strong>Results: </strong>Overall and fluid cognition composite ANOVAs revealed significant effects of time (<i>p</i> <.01), but not group (<i>p</i> >.22). Working memory (<i>p</i> = .04; <i>d</i> = 0.49) and processing speed (<i>p</i> <.01; <i>d</i> = 0.67) models indicated significant time effects. Models analyzing individual neurocognitive domains did not reveal significant group effects (<i>p</i> >.05). Models examining crystalized cognition did not reveal significant effects of group (<i>p</i> >.10), time (<i>p</i> >.12), or interaction (<i>p</i> >.35).</p><p><strong>Conclusions: </strong>These results did not indicate unique weaknesses in fluid cognition, concerning for NIHTB-CB's sensitivity in detecting post-injury changes using an OI control group. The NIHTB-CB captured preserved crystallized cognition throughout recovery as hypothesized.</p>","PeriodicalId":8047,"journal":{"name":"Applied Neuropsychology: Child","volume":" ","pages":"1-10"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Neurocognitive evaluation of adolescents recovering from sports-related concussion: A prospective cohort pilot study utilizing the National Institutes of Health Toolbox cognition Battery.\",\"authors\":\"Lauren N Irwin Harper, Julia C Nahman, Luis Ahumada, Mohamed Rehman, Sarah Irani, P Patrick Mularoni, Danielle M Ransom\",\"doi\":\"10.1080/21622965.2025.2507326\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study explored NIHTB-CB's utility in assessing cognitive recovery in adolescents with SRC. We hypothesized the NIHTB-CB is sensitive to detecting weaknesses in fluid, but not crystalized, cognition, and adolescents recovering from SRC exhibit greater weaknesses than orthopedically injured (OI) adolescents.</p><p><strong>Method: </strong>Thirty-six participants diagnosed with SRC or OI were enrolled in a pilot study and completed the NIHTB-CB at the time of enrollment and 4-6 weeks post-injury clearance. A total of 14 participants were excluded from analyses due to attrition (<i>n</i> = 4) and PVT failure (<i>n</i> = 10), with 22 participants included in final analyses (SRC <i>n</i> = 10; OI <i>n =</i> 12).</p><p><strong>Results: </strong>Overall and fluid cognition composite ANOVAs revealed significant effects of time (<i>p</i> <.01), but not group (<i>p</i> >.22). Working memory (<i>p</i> = .04; <i>d</i> = 0.49) and processing speed (<i>p</i> <.01; <i>d</i> = 0.67) models indicated significant time effects. Models analyzing individual neurocognitive domains did not reveal significant group effects (<i>p</i> >.05). Models examining crystalized cognition did not reveal significant effects of group (<i>p</i> >.10), time (<i>p</i> >.12), or interaction (<i>p</i> >.35).</p><p><strong>Conclusions: </strong>These results did not indicate unique weaknesses in fluid cognition, concerning for NIHTB-CB's sensitivity in detecting post-injury changes using an OI control group. The NIHTB-CB captured preserved crystallized cognition throughout recovery as hypothesized.</p>\",\"PeriodicalId\":8047,\"journal\":{\"name\":\"Applied Neuropsychology: Child\",\"volume\":\" \",\"pages\":\"1-10\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Neuropsychology: Child\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1080/21622965.2025.2507326\",\"RegionNum\":4,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Neuropsychology: Child","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/21622965.2025.2507326","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的：探讨NIHTB-CB在评估青少年SRC认知恢复中的应用价值。我们假设NIHTB-CB对液体认知缺陷敏感，但对结晶认知缺陷不敏感，并且从SRC中恢复的青少年比骨科损伤（OI）的青少年表现出更大的缺陷。方法：36名诊断为SRC或成骨不全的参与者被纳入一项试点研究，并在入组时和损伤清除后4-6周完成NIHTB-CB。由于磨耗（n = 4）和PVT失败（n = 10），共有14名参与者被排除在分析之外，22名参与者被纳入最终分析(SRC n = 10；OI n = 12)。结果：整体认知和流体认知综合方差分析显示时间有显著影响（p p >.22）。工作记忆(p = .04；D = 0.49)和处理速度（p D = 0.67）模型显示出显著的时间效应。分析个体神经认知域的模型没有显示显著的组效应（p >.05）。检验结晶认知的模型没有显示出群体（p >.10）、时间（p >.12）或相互作用（p >.35）的显著影响。结论：这些结果并没有表明液体认知的独特弱点，这与NIHTB-CB在使用OI对照组检测损伤后变化的敏感性有关。NIHTB-CB在整个恢复过程中捕获了保留的结晶认知，这是假设的。
Neurocognitive evaluation of adolescents recovering from sports-related concussion: A prospective cohort pilot study utilizing the National Institutes of Health Toolbox cognition Battery.
Objective: This study explored NIHTB-CB's utility in assessing cognitive recovery in adolescents with SRC. We hypothesized the NIHTB-CB is sensitive to detecting weaknesses in fluid, but not crystalized, cognition, and adolescents recovering from SRC exhibit greater weaknesses than orthopedically injured (OI) adolescents.
Method: Thirty-six participants diagnosed with SRC or OI were enrolled in a pilot study and completed the NIHTB-CB at the time of enrollment and 4-6 weeks post-injury clearance. A total of 14 participants were excluded from analyses due to attrition (n = 4) and PVT failure (n = 10), with 22 participants included in final analyses (SRC n = 10; OI n = 12).
Results: Overall and fluid cognition composite ANOVAs revealed significant effects of time (p <.01), but not group (p >.22). Working memory (p = .04; d = 0.49) and processing speed (p <.01; d = 0.67) models indicated significant time effects. Models analyzing individual neurocognitive domains did not reveal significant group effects (p >.05). Models examining crystalized cognition did not reveal significant effects of group (p >.10), time (p >.12), or interaction (p >.35).
Conclusions: These results did not indicate unique weaknesses in fluid cognition, concerning for NIHTB-CB's sensitivity in detecting post-injury changes using an OI control group. The NIHTB-CB captured preserved crystallized cognition throughout recovery as hypothesized.
期刊介绍：
Applied Neuropsychology: Child publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in children. Full-length articles and brief communications are included. Case studies of child patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.
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