Nicola Man, Jane Akhurst, Olivia Price, Agata Chrzanowska, Rachel Sutherland, Paul M. Dietze, Raimondo Bruno, Louisa Degenhardt, Wing See Yuen, Lauren Moran, Louise Tierney, Amy Peacock
{"title":"在澳大利亚COVID-19大流行的第一年,药物引起的住院和死亡的变化","authors":"Nicola Man, Jane Akhurst, Olivia Price, Agata Chrzanowska, Rachel Sutherland, Paul M. Dietze, Raimondo Bruno, Louisa Degenhardt, Wing See Yuen, Lauren Moran, Louise Tierney, Amy Peacock","doi":"10.1111/dar.14088","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p>We aimed to determine whether the trend in the rate of drug-induced hospitalisations and deaths changed during the first year of the COVID-19 pandemic in Australia.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Data comprised crude monthly rates (per 1,000,000 persons) of hospitalisations and deaths directly attributable to illicit drugs, prescription medicines, or medicines available without a prescription, nationally from 2011 to 2021. Observed rates during the COVID-19 pandemic (2020–2021) were compared with their counterfactual forecast in an ARIMA model, overall and disaggregated by sex, age and drug involved.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Observed rates of drug-induced hospitalisation and death, overall and by sex, were not significantly different from the forecasted rates. The rates of drug-induced death among people aged 35–54 and 55+ years were lower than forecasted by 2.1 [95% prediction interval = −3.8, −0.4] and 0.7 [−1.3, −0.1] deaths per 1,000,000 persons per month, respectively. The rates of drug-induced hospitalisation and death involving heroin were lower than forecasted by 1.5 [−2.4, −0.7] and 1.0 [−1.3, −0.6] per 1,000,000 persons per month, respectively, as were those involving amphetamine-type stimulants by 12.4 [−21.4, −0.8] and 0.5 [−0.7, −0.2] per 1,000,000 persons per month, respectively. The rate of cannabinoid-induced hospitalisations was higher than forecasted by 3.8 [0.8, 6.8] hospitalisations per 1,000,000 persons per month.</p>\n </section>\n \n <section>\n \n <h3> Discussion and Conclusions</h3>\n \n <p>We found no evidence of an overall difference in the rate of drug-induced harms during the COVID-19 pandemic relative to the forecasted trend. However, there were differences by drug involved, which may be explained by drug market disruptions and changes in drug use during the pandemic.</p>\n </section>\n </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"44 5","pages":"1419-1429"},"PeriodicalIF":2.6000,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.14088","citationCount":"0","resultStr":"{\"title\":\"Changes in Drug-Induced Hospitalisations and Deaths During the First Year of the COVID-19 Pandemic in Australia\",\"authors\":\"Nicola Man, Jane Akhurst, Olivia Price, Agata Chrzanowska, Rachel Sutherland, Paul M. 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Observed rates during the COVID-19 pandemic (2020–2021) were compared with their counterfactual forecast in an ARIMA model, overall and disaggregated by sex, age and drug involved.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Observed rates of drug-induced hospitalisation and death, overall and by sex, were not significantly different from the forecasted rates. The rates of drug-induced death among people aged 35–54 and 55+ years were lower than forecasted by 2.1 [95% prediction interval = −3.8, −0.4] and 0.7 [−1.3, −0.1] deaths per 1,000,000 persons per month, respectively. The rates of drug-induced hospitalisation and death involving heroin were lower than forecasted by 1.5 [−2.4, −0.7] and 1.0 [−1.3, −0.6] per 1,000,000 persons per month, respectively, as were those involving amphetamine-type stimulants by 12.4 [−21.4, −0.8] and 0.5 [−0.7, −0.2] per 1,000,000 persons per month, respectively. 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Changes in Drug-Induced Hospitalisations and Deaths During the First Year of the COVID-19 Pandemic in Australia
Introduction
We aimed to determine whether the trend in the rate of drug-induced hospitalisations and deaths changed during the first year of the COVID-19 pandemic in Australia.
Methods
Data comprised crude monthly rates (per 1,000,000 persons) of hospitalisations and deaths directly attributable to illicit drugs, prescription medicines, or medicines available without a prescription, nationally from 2011 to 2021. Observed rates during the COVID-19 pandemic (2020–2021) were compared with their counterfactual forecast in an ARIMA model, overall and disaggregated by sex, age and drug involved.
Results
Observed rates of drug-induced hospitalisation and death, overall and by sex, were not significantly different from the forecasted rates. The rates of drug-induced death among people aged 35–54 and 55+ years were lower than forecasted by 2.1 [95% prediction interval = −3.8, −0.4] and 0.7 [−1.3, −0.1] deaths per 1,000,000 persons per month, respectively. The rates of drug-induced hospitalisation and death involving heroin were lower than forecasted by 1.5 [−2.4, −0.7] and 1.0 [−1.3, −0.6] per 1,000,000 persons per month, respectively, as were those involving amphetamine-type stimulants by 12.4 [−21.4, −0.8] and 0.5 [−0.7, −0.2] per 1,000,000 persons per month, respectively. The rate of cannabinoid-induced hospitalisations was higher than forecasted by 3.8 [0.8, 6.8] hospitalisations per 1,000,000 persons per month.
Discussion and Conclusions
We found no evidence of an overall difference in the rate of drug-induced harms during the COVID-19 pandemic relative to the forecasted trend. However, there were differences by drug involved, which may be explained by drug market disruptions and changes in drug use during the pandemic.
期刊介绍:
Drug and Alcohol Review is an international meeting ground for the views, expertise and experience of all those involved in studying alcohol, tobacco and drug problems. Contributors to the Journal examine and report on alcohol and drug use from a wide range of clinical, biomedical, epidemiological, psychological and sociological perspectives. Drug and Alcohol Review particularly encourages the submission of papers which have a harm reduction perspective. However, all philosophies will find a place in the Journal: the principal criterion for publication of papers is their quality.