在澳大利亚COVID-19大流行的第一年,药物引起的住院和死亡的变化

IF 2.6 3区 医学 Q2 SUBSTANCE ABUSE
Nicola Man, Jane Akhurst, Olivia Price, Agata Chrzanowska, Rachel Sutherland, Paul M. Dietze, Raimondo Bruno, Louisa Degenhardt, Wing See Yuen, Lauren Moran, Louise Tierney, Amy Peacock
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引用次数: 0

摘要

前言:我们旨在确定在澳大利亚COVID-19大流行的第一年,药物引起的住院率和死亡率的趋势是否发生了变化。方法:数据包括2011年至2021年全国范围内直接归因于非法药物、处方药或无处方药物的住院和死亡的粗月比率(每100万人)。将2019冠状病毒病大流行(2020-2021年)期间观察到的发病率与ARIMA模型中的反事实预测进行了总体比较,并按性别、年龄和所涉药物分类。结果:观察到的药物引起的住院率和死亡率,总体上和按性别划分,与预测率没有显著差异。35-54岁和55岁以上人群的药物所致死亡率分别低于预测值2.1(95%预测区间= -3.8,-0.4)和0.7(95%预测区间= -1.3,-0.1)/ 100万人。涉及海洛因的药物引起的住院率和死亡率比预测的每月每100万人分别低1.5[-2.4,-0.7]和1.0[-1.3,-0.6],而涉及安非他明类兴奋剂的药物引起的住院率和死亡率比预测的每月每100万人分别低12.4[-21.4,-0.8]和0.5[-0.7,-0.2]。大麻素引起的住院率高于预测的3.8[0.8,6.8]住院每100万人每月。讨论和结论:我们没有发现证据表明在COVID-19大流行期间药物致伤率与预测趋势存在总体差异。但是,所涉药物不同,情况也有所不同,这可能是由于大流行期间药物市场的中断和药物使用的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Changes in Drug-Induced Hospitalisations and Deaths During the First Year of the COVID-19 Pandemic in Australia

Changes in Drug-Induced Hospitalisations and Deaths During the First Year of the COVID-19 Pandemic in Australia

Introduction

We aimed to determine whether the trend in the rate of drug-induced hospitalisations and deaths changed during the first year of the COVID-19 pandemic in Australia.

Methods

Data comprised crude monthly rates (per 1,000,000 persons) of hospitalisations and deaths directly attributable to illicit drugs, prescription medicines, or medicines available without a prescription, nationally from 2011 to 2021. Observed rates during the COVID-19 pandemic (2020–2021) were compared with their counterfactual forecast in an ARIMA model, overall and disaggregated by sex, age and drug involved.

Results

Observed rates of drug-induced hospitalisation and death, overall and by sex, were not significantly different from the forecasted rates. The rates of drug-induced death among people aged 35–54 and 55+ years were lower than forecasted by 2.1 [95% prediction interval = −3.8, −0.4] and 0.7 [−1.3, −0.1] deaths per 1,000,000 persons per month, respectively. The rates of drug-induced hospitalisation and death involving heroin were lower than forecasted by 1.5 [−2.4, −0.7] and 1.0 [−1.3, −0.6] per 1,000,000 persons per month, respectively, as were those involving amphetamine-type stimulants by 12.4 [−21.4, −0.8] and 0.5 [−0.7, −0.2] per 1,000,000 persons per month, respectively. The rate of cannabinoid-induced hospitalisations was higher than forecasted by 3.8 [0.8, 6.8] hospitalisations per 1,000,000 persons per month.

Discussion and Conclusions

We found no evidence of an overall difference in the rate of drug-induced harms during the COVID-19 pandemic relative to the forecasted trend. However, there were differences by drug involved, which may be explained by drug market disruptions and changes in drug use during the pandemic.

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来源期刊
Drug and alcohol review
Drug and alcohol review SUBSTANCE ABUSE-
CiteScore
4.80
自引率
10.50%
发文量
151
期刊介绍: Drug and Alcohol Review is an international meeting ground for the views, expertise and experience of all those involved in studying alcohol, tobacco and drug problems. Contributors to the Journal examine and report on alcohol and drug use from a wide range of clinical, biomedical, epidemiological, psychological and sociological perspectives. Drug and Alcohol Review particularly encourages the submission of papers which have a harm reduction perspective. However, all philosophies will find a place in the Journal: the principal criterion for publication of papers is their quality.
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