中国老年人主食类型与心血管疾病风险的关系

IF 4 2区 农林科学 Q2 NUTRITION & DIETETICS
Frontiers in Nutrition Pub Date : 2025-05-22 eCollection Date: 2025-01-01 DOI:10.3389/fnut.2025.1539920
Chunmei Chen, Fayun Zhao, Maozong Du, Xin Wang
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引用次数: 0

摘要

背景:饮食习惯,特别是主食消费,在影响心血管疾病(CVD)风险中起着重要作用。然而,关于主食类型与老年人群心血管疾病发病率之间关系的研究有限,特别是在中国。本研究旨在确定哪些类型的主食对中国老年人的心血管健康最有益。方法:分析中国纵向健康寿命调查(CLHLS)的数据,探讨主食类型(大米、小麦和粗粮)与65岁及以上成年人心血管疾病风险之间的关系。采用Cox比例风险模型评估主食种类与心血管疾病发病率之间的关系,而限制三次样条曲线评估主食摄入量与心血管疾病风险之间潜在的非线性关系。根据年龄、性别和高血压病史进行分层分析。结果:在中位随访7.38 年期间,1757名参与者出现了新发CVD。小麦作为主食与患心血管疾病的风险比大米高40.8% (HR: 1.408;95% ci: 1.195-1.658;p 结论:这项研究强调了主食类型对心血管疾病风险的差异影响,与大米相比,小麦消费与心血管疾病的发病率相关,特别是在特定的亚组中。这些发现为中国老年人的饮食指南提供了证据,并强调了对潜在机制进行进一步研究的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between staple food types and cardiovascular disease risk among older Chinese adults.

Background: Dietary habits, particularly staple food consumption, play a significant role in influencing cardiovascular disease (CVD) risk. However, limited research has examined the relationship between staple food types and CVD incidence in aging populations, especially in China. This study aims to identify which types of staple foods are most beneficial for cardiovascular health among older Chinese adults.

Methods: Data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were analyzed to explore the associations between staple food types (rice, wheat, and coarse cereals) and CVD risk among 16,498 adults aged 65 and older. Cox proportional hazards models were employed to evaluate the relationship between staple food types and CVD incidence, while restricted cubic splines assessed potential non-linear relationships between staple food intake and CVD risk. Stratified analyses were performed based on age, sex, and hypertension history.

Results: During a median follow-up of 7.38 years, 1757 participants experienced new-onset CVD. Wheat as a staple food was related to a 40.8% higher risk of CVD compared to rice (HR: 1.408; 95% CI: 1.195-1.658; p < 0.001), while no significant association was observed for coarse cereals. Stratified analyses revealed that the association with wheat was stronger among participants aged 65-79 years, males, and those without hypertension. No linear relationship was found between intake levels of rice, wheat, or coarse cereals and CVD risk, but non-linear associations emerged for rice and wheat intake (P for non-linear association<0.001 and = 0.010, respectively). A U-shaped relationship was observed for wheat, with the lowest CVD risk at a cooked intake of 375 g/day, consistent with dietary guidelines.

Conclusion: This study highlights the differential impact of staple food types on CVD risk, with wheat consumption linked to a higher incidence of CVD compared to rice, particularly in specific subgroups. These findings provide evidence to inform dietary guidelines for older Chinese adults and underscore the need for further research into the underlying mechanisms.

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来源期刊
Frontiers in Nutrition
Frontiers in Nutrition Agricultural and Biological Sciences-Food Science
CiteScore
5.20
自引率
8.00%
发文量
2891
审稿时长
12 weeks
期刊介绍: No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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