Simar Singh, Sasha Gorrell, Catherine R. Drury, Alan Duffy, Philip S. Mehler, Kianna Zucker, Daniel Le Grange, Erin E. Reilly, Renee D. Rienecke
{"title":"青少年神经性厌食症患者早期体重趋势对住院治疗结果的影响。","authors":"Simar Singh, Sasha Gorrell, Catherine R. Drury, Alan Duffy, Philip S. Mehler, Kianna Zucker, Daniel Le Grange, Erin E. Reilly, Renee D. Rienecke","doi":"10.1002/eat.24480","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Weight variability (WV), or daily-to-weekly fluctuations in weight, associates with increased eating pathology in adults with bulimia nervosa and greater weight gain across the developmental span in healthy controls, but few studies have explored these relations in adolescents with anorexia nervosa (AN). Given the importance of early weight gain during treatment for AN prognosis, WV could impact outcomes via effects on weight trends and related psychopathology. The current study examined whether WV and the slope of weight change predict eating disorder symptoms at the end of treatment (EOT) among adolescents with AN.</p>\n </section>\n \n <section>\n \n <h3> Method</h3>\n \n <p>Adolescents with AN (<i>N</i> = 284) receiving residential treatment completed the Eating Disorder Examination Questionnaire (EDE-Q) at admission and EOT. WV was calculated using the root-mean-squared-error of daily weights over the first 14 days of treatment. Linear regressions examined the effect of WV, slope of weight change over 14 days, and their interaction on percent expected body weight (%EBW) and EDE-Q scores at EOT.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>WV positively predicted EDE-Q Global Score (<i>p</i> = 0.033, <i>sr</i>\n <sup>\n <i>2</i>\n </sup> = 0.01), Shape Concern (<i>p</i> = 0.026, <i>sr</i>\n <sup>\n <i>2</i>\n </sup> = 0.01), and Weight Concern (<i>p</i> = 0.008, <i>sr</i>\n <sup>\n <i>2</i>\n </sup> = 0.02) at EOT. Neither WV nor the slope of weight change predicted %EBW at EOT (<i>p</i>s > 0.05). The slope of weight change did not predict EDE-Q, nor did it moderate the relation between WV and any outcomes (<i>p</i>s > 0.05).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Patients who experience greater weight fluctuations early in treatment may be more susceptible to elevated psychopathology at discharge. In light of few significant effects and small effect sizes, more research is needed to determine the putative role of early weight trends in adolescent AN outcomes.</p>\n </section>\n </div>","PeriodicalId":51067,"journal":{"name":"International Journal of Eating Disorders","volume":"58 9","pages":"1758-1768"},"PeriodicalIF":4.3000,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of Early Weight Trends on Residential Treatment Outcomes Among Adolescents With Anorexia Nervosa\",\"authors\":\"Simar Singh, Sasha Gorrell, Catherine R. Drury, Alan Duffy, Philip S. Mehler, Kianna Zucker, Daniel Le Grange, Erin E. Reilly, Renee D. Rienecke\",\"doi\":\"10.1002/eat.24480\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Weight variability (WV), or daily-to-weekly fluctuations in weight, associates with increased eating pathology in adults with bulimia nervosa and greater weight gain across the developmental span in healthy controls, but few studies have explored these relations in adolescents with anorexia nervosa (AN). Given the importance of early weight gain during treatment for AN prognosis, WV could impact outcomes via effects on weight trends and related psychopathology. The current study examined whether WV and the slope of weight change predict eating disorder symptoms at the end of treatment (EOT) among adolescents with AN.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Method</h3>\\n \\n <p>Adolescents with AN (<i>N</i> = 284) receiving residential treatment completed the Eating Disorder Examination Questionnaire (EDE-Q) at admission and EOT. WV was calculated using the root-mean-squared-error of daily weights over the first 14 days of treatment. Linear regressions examined the effect of WV, slope of weight change over 14 days, and their interaction on percent expected body weight (%EBW) and EDE-Q scores at EOT.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>WV positively predicted EDE-Q Global Score (<i>p</i> = 0.033, <i>sr</i>\\n <sup>\\n <i>2</i>\\n </sup> = 0.01), Shape Concern (<i>p</i> = 0.026, <i>sr</i>\\n <sup>\\n <i>2</i>\\n </sup> = 0.01), and Weight Concern (<i>p</i> = 0.008, <i>sr</i>\\n <sup>\\n <i>2</i>\\n </sup> = 0.02) at EOT. Neither WV nor the slope of weight change predicted %EBW at EOT (<i>p</i>s > 0.05). The slope of weight change did not predict EDE-Q, nor did it moderate the relation between WV and any outcomes (<i>p</i>s > 0.05).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Patients who experience greater weight fluctuations early in treatment may be more susceptible to elevated psychopathology at discharge. 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Effects of Early Weight Trends on Residential Treatment Outcomes Among Adolescents With Anorexia Nervosa
Background
Weight variability (WV), or daily-to-weekly fluctuations in weight, associates with increased eating pathology in adults with bulimia nervosa and greater weight gain across the developmental span in healthy controls, but few studies have explored these relations in adolescents with anorexia nervosa (AN). Given the importance of early weight gain during treatment for AN prognosis, WV could impact outcomes via effects on weight trends and related psychopathology. The current study examined whether WV and the slope of weight change predict eating disorder symptoms at the end of treatment (EOT) among adolescents with AN.
Method
Adolescents with AN (N = 284) receiving residential treatment completed the Eating Disorder Examination Questionnaire (EDE-Q) at admission and EOT. WV was calculated using the root-mean-squared-error of daily weights over the first 14 days of treatment. Linear regressions examined the effect of WV, slope of weight change over 14 days, and their interaction on percent expected body weight (%EBW) and EDE-Q scores at EOT.
Results
WV positively predicted EDE-Q Global Score (p = 0.033, sr2 = 0.01), Shape Concern (p = 0.026, sr2 = 0.01), and Weight Concern (p = 0.008, sr2 = 0.02) at EOT. Neither WV nor the slope of weight change predicted %EBW at EOT (ps > 0.05). The slope of weight change did not predict EDE-Q, nor did it moderate the relation between WV and any outcomes (ps > 0.05).
Conclusions
Patients who experience greater weight fluctuations early in treatment may be more susceptible to elevated psychopathology at discharge. In light of few significant effects and small effect sizes, more research is needed to determine the putative role of early weight trends in adolescent AN outcomes.
期刊介绍：
Articles featured in the journal describe state-of-the-art scientific research on theory, methodology, etiology, clinical practice, and policy related to eating disorders, as well as contributions that facilitate scholarly critique and discussion of science and practice in the field. Theoretical and empirical work on obesity or healthy eating falls within the journal’s scope inasmuch as it facilitates the advancement of efforts to describe and understand, prevent, or treat eating disorders. IJED welcomes submissions from all regions of the world and representing all levels of inquiry (including basic science, clinical trials, implementation research, and dissemination studies), and across a full range of scientific methods, disciplines, and approaches.
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