揭示手性量子点在细胞内吞过程中的时空行为

IF 6.7 1区化学 Q1 CHEMISTRY, ANALYTICAL

Analytical Chemistry Pub Date : 2025-06-05 DOI:10.1021/acs.analchem.4c06030

Shoupeng Wang, Weiheng Kong, Bangming Wang, He Li, Huaijiang Li, Hui Zhang, Yan Zhao, Fengli Qu

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引用次数: 0

摘要

手性量子点的内吞作用是其与生物系统相互作用的关键初始步骤，对后续的生物效应有重要影响。在这项研究中，我们深入研究了手性量子点在细胞内吞过程中的作用机制。结果表明，手性量子点在内吞过程中表现出显著差异，即使它们的物理化学性质相似。通过对比分析，可以更好地了解手性量子点的生物学效应，为纳米材料的安全性评价及其在生物医学领域的应用提供科学指导。此外，手性量子点在生物体水平上的生物学行为表现出明显的手性依赖性，这为手性纳米材料在生物医学中的应用提供了重要的理论基础，并为未来的研究和应用开辟了新的方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Unveiling the Spatiotemporal Behavior of Chiral Quantum Dots During Cellular Endocytosis

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Unveiling the Spatiotemporal Behavior of Chiral Quantum Dots During Cellular Endocytosis

The endocytosis of chiral quantum dots is the key initial step in their interaction with biological systems, and it significantly influences subsequent biological effects. In this study, we delve into the mechanism of chiral quantum dots during the process of cellular endocytosis. The results reveal that chiral quantum dots exhibit significant differences in the endocytosis process, even when their physicochemical properties are similar. Through comparative analysis, we can better understand the biological effects of chiral quantum dots and provide scientific guidance for the safety assessment of nanomaterials and their application in the field of biomedicine. Furthermore, the biological behavior of chiral quantum dots at the organism level shows a distinct chirality dependence, which provides an important theoretical basis for the application of chiral nanomaterials in biomedicine and opens up new directions for future research and application.

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来源期刊

Analytical Chemistry 化学-分析化学

CiteScore

12.10

自引率

12.20%

发文量

1949

审稿时长

1.4 months

期刊介绍： Analytical Chemistry, a peer-reviewed research journal, focuses on disseminating new and original knowledge across all branches of analytical chemistry. Fundamental articles may explore general principles of chemical measurement science and need not directly address existing or potential analytical methodology. They can be entirely theoretical or report experimental results. Contributions may cover various phases of analytical operations, including sampling, bioanalysis, electrochemistry, mass spectrometry, microscale and nanoscale systems, environmental analysis, separations, spectroscopy, chemical reactions and selectivity, instrumentation, imaging, surface analysis, and data processing. Papers discussing known analytical methods should present a significant, original application of the method, a notable improvement, or results on an important analyte.