{"title":"hUSI是一个强大的基于转录组的细胞衰老预测工具。","authors":"","doi":"10.1038/s43587-025-00894-2","DOIUrl":null,"url":null,"abstract":"Human universal senescence index (hUSI) is a data-driven scoring tool that is derived from the most comprehensive senescence transcriptome data available. Demonstrating excellent accuracy and robustness across cells under various conditions, hUSI identified unknown senescence regulators and served as a reliable senescence scoring method in aging research and the clinical assessment of age-related diseases.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":"5 6","pages":"966-967"},"PeriodicalIF":19.4000,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"hUSI is a robust transcriptome-based cellular senescence prediction tool\",\"authors\":\"\",\"doi\":\"10.1038/s43587-025-00894-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Human universal senescence index (hUSI) is a data-driven scoring tool that is derived from the most comprehensive senescence transcriptome data available. Demonstrating excellent accuracy and robustness across cells under various conditions, hUSI identified unknown senescence regulators and served as a reliable senescence scoring method in aging research and the clinical assessment of age-related diseases.\",\"PeriodicalId\":94150,\"journal\":{\"name\":\"Nature aging\",\"volume\":\"5 6\",\"pages\":\"966-967\"},\"PeriodicalIF\":19.4000,\"publicationDate\":\"2025-06-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature aging\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s43587-025-00894-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-025-00894-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
hUSI is a robust transcriptome-based cellular senescence prediction tool
Human universal senescence index (hUSI) is a data-driven scoring tool that is derived from the most comprehensive senescence transcriptome data available. Demonstrating excellent accuracy and robustness across cells under various conditions, hUSI identified unknown senescence regulators and served as a reliable senescence scoring method in aging research and the clinical assessment of age-related diseases.
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