Nature aging

Extracellular vesicles from antler blastema progenitor cells reverse bone loss and mitigate aging-related phenotypes in mice and macaques.

Pub Date : 2025-07-14 DOI: 10.1038/s43587-025-00918-x Yiming Hao, Beibei Yu, Mingze Qin, Tao Qin, Jianhong Wang, Yitao Wei, Chengxiang Zhao, Yaowen Xing, Yuan Yuan, Tingfeng Xue, Borui Xue, Yali Zhang, Hongdi Huang, Xiaomei Yu, Yunchao Ji, Minghao Qiu, Yufang Zhou, Bing Xia, Teng Ma, Shengyou Li, Haining Wu, Xue Gao, Yujie Yang, Lingli Guo, Yongfeng Zhang, Zhenguo Wang, Huiling Sun, Xueli Gao, Zujian Huang, Longbao Lv, Dongdong Wu, Zhipeng Li, Yonggang Yao, Wen Wang, Zhuojing Luo, Qiang Qiu, Jinghui Huang

Rethinking inflammaging across human diversity.

Pub Date : 2025-07-14 DOI: 10.1038/s43587-025-00933-y Marina Terekhova, Maxim Artyomov

Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice.

Pub Date : 2025-07-14 DOI: 10.1038/s43587-025-00889-z Krystyna Mazan-Mamczarz, Dimitrios Tsitsipatis, Bennett G Childs, Angelica E Carr, Carla Rocha Dos Santos, Carlos Anerillas, Brigette Romero, Jordan M Gregg, Charnae' Henry-Smith, Ada N Okereke, Marc Michel, Rachel Munk, Jennifer L Martindale, Yulan Piao, Jinshui Fan, Maria O Hernandez, Noemi Kedei, Michael L Viacheslavov, Madeline M F Wong, Olga V Fedorova, Mona Batish, Supriyo De, Darren J Baker, Myriam Gorospe, Allison B Herman