早期饲喂技术对肉鸡生产性能、脂质氧化及免疫相关基因表达的影响

IF 3.8 1区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Poultry Science Pub Date : 2025-05-26 DOI:10.1016/j.psj.2025.105335

Virág Ács , Nóra Szeli , József Nagy , Szilvia Áprily , Annamária Tischler , Orsolya Csötönyi , Ildikó Jócsák , Ildikó Benedek , Örs Petneházy , Janka Turbók , Judit Enyezdi , Veronika Halas

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引用次数: 0

摘要

本试验研究了在蛋饲中添加dl -蛋氨酸和孵化后添加水凝胶®，以研究早期饲养对商品肉鸡生产性能和免疫相关性状的影响。取1120个Ross 308卵，分为7个处理组：完整（不给蛋）和立即获得饲料（C1），盐水处理和立即获得饲料（C2），完整和延迟喂养（ID），盐水处理和延迟喂养（IoS）， dl -蛋氨酸处理和延迟喂养（IoM），完整和延迟获得饲料，但在孵化后立即获得不含（Hyd）或含有5mg/kg (HydM) dl -蛋氨酸的商业水凝胶®。结果表明，蛋氨酸对蛋鸡增重有积极作用(p <；0.001)，然而，与商业水凝胶®相比，它无法与即时喂食竞争。嗜异性生殖细胞数量显著减少(p <；0.001)，第21天的ID和IoS与立即喂食对照组（C1）相比。补充蛋氨酸组淋巴细胞、单核细胞和嗜酸性粒细胞数量增加(p <；0.05) （IoM, HydM）表明免疫保护增强。各组总抗氧化能力（FRAP）和丙二醛浓度（MDA）差异无统计学意义（p = 0.07）。细胞色素P450 H1 （CYP2H1）基因在所有治疗组（第21天和第35天）均下调，表明代谢较慢，特别是与C1和C2相比，ID组(p <；0.001)。HydM处理可在第35天上调il - 2表达，而IoM处理在第35天显著下调il - 2表达(p <；0.001)。所有治疗组il - 6均上调(p <；0.001)，除了HydM，其中基因表达与管家基因没有差异。早期饲粮中添加蛋氨酸对生产性能和免疫系统有积极影响，然而，没有一种早期饲养方法能与即时饲料获取相竞争。早期营养可能产生的积极作用及其对表观遗传的影响有待进一步研究。

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Effects of early feeding technologies providing methionine supplementation on performance, lipid oxidation, and some immune-related gene expression in broiler chicken

In ovo administration of DL-methionine and post-hatch Hydrogel® supplements were tested to examine the impact of early feeding on performance and immune-related traits in a commercial broiler stock. One thousand one hundred and twenty Ross 308 eggs were incubated and assigned to seven treatment groups: intact (no in ovo administration) and immediate feed access (C1), in ovo saline treatment and immediate feed access (C2), intact and delayed feeding (ID), in ovo saline treatment and delayed feeding (IoS), in ovo DL-Methionine treatment and delayed feeding (IoM), intact and delayed access to feed, but immediate access to commercial Hydrogel® without (Hyd) or with 5mg/kg (HydM) DL-methionine post-hatch. The results showed, that the in-ovo methionine may have positive effects on the weight gain of the birds (p < 0.001) compared to the commercial Hydrogel® however, it cannot compete with the immediate feeding. The number of heterophils decreased significantly (p < 0.001) by day 21 in ID and IoS compared to the immediately fed control (C1). The number of lymphocytes, monocytes, and eosinophils, increased in treatments supplemented with methionine (p < 0.05) (IoM, HydM) indicating enhanced immune protection.

There were no differences in the total antioxidant capacity (FRAP) and malonaldehyde concentration (MDA) (p = 0.07) in the examined groups. The Cytochrome P450 H1 (CYP2H1) gene was downregulated in all treatment groups (on days 21 and 35) indicating a slower metabolism, particularly in the ID group compared to C1 and C2 (p < 0.001). The HydM treatment could upregulate the IL2 expression as the immediate feeding, while only IoM treatment resulted in significant downregulation by day 35 (p < 0.001). IL6 was upregulated in all treatment groups (p < 0.001) except for HydM, where the gene expression did not differ from the housekeeping gene. Early administration of dietary methionine has a positive effect on performance and the immune system, however, none of the early feeding methods can compete with immediate feed access. The possible positive effects of early nutrition and its epigenetic impact should be examined in further studies.

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来源期刊

Poultry Science 农林科学-奶制品与动物科学

CiteScore

7.60

自引率

15.90%

发文量

审稿时长

94 days

期刊介绍： First self-published in 1921, Poultry Science is an internationally renowned monthly journal, known as the authoritative source for a broad range of poultry information and high-caliber research. The journal plays a pivotal role in the dissemination of preeminent poultry-related knowledge across all disciplines. As of January 2020, Poultry Science will become an Open Access journal with no subscription charges, meaning authors who publish here can make their research immediately, permanently, and freely accessible worldwide while retaining copyright to their work. Papers submitted for publication after October 1, 2019 will be published as Open Access papers. An international journal, Poultry Science publishes original papers, research notes, symposium papers, and reviews of basic science as applied to poultry. This authoritative source of poultry information is consistently ranked by ISI Impact Factor as one of the top 10 agriculture, dairy and animal science journals to deliver high-caliber research. Currently it is the highest-ranked (by Impact Factor and Eigenfactor) journal dedicated to publishing poultry research. Subject areas include breeding, genetics, education, production, management, environment, health, behavior, welfare, immunology, molecular biology, metabolism, nutrition, physiology, reproduction, processing, and products.