老年女性肌肉减少症患者蛋白质摄入在维持肌肉质量组成中的作用。

IF 4 2区 农林科学 Q2 NUTRITION & DIETETICS
Frontiers in Nutrition Pub Date : 2025-05-12 eCollection Date: 2025-01-01 DOI:10.3389/fnut.2025.1547325
Izwa Ishaq, Sana Noreen, Patrick Maduabuchi Aja, Ayomide Victor Atoki
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引用次数: 0

摘要

膳食蛋白质对于保持肌肉质量和促进长期骨骼健康至关重要,尤其是在老年人中。本研究的新颖之处在于评估不同蛋白质摄入水平(0.8 vs. 1.2 g/kg b.w/d)对患有肌肉减少症的老年女性肌肉质量组成的影响。为此,在本研究试验中,共有126名参与者(60-75 岁)被招募,并平均分为两组:正常蛋白质摄入量(0.8 g/kg b.w/d)和中高蛋白质摄入量(1.2 g/kg b.w/d),持续12 周。通过人体测量、磁共振成像(MRI)、握力和膝关节屈曲测试以及基线和干预后比较来评估饮食蛋白质的影响。采用SPSS软件进行统计分析,采用配对样本t检验,p 2 × 104)和大腿(258.04 ± 7.26 MCSA, mm2 × 104)的显著性水平进一步证实了增加蛋白质摄入量的积极影响。该研究得出结论,适度高蛋白饮食可以有效地支持老年女性肌肉减少症患者的肌肉健康。因此,摄入足够的蛋白质可以作为一种战略性的营养干预措施,以减轻老年妇女的肌肉损失和改善整体身体功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of protein intake in maintaining muscle mass composition among elderly females suffering from sarcopenia.

Dietary protein is crucial in preserving muscle mass and promoting long-term bone health, particularly in aging populations. The novelty of this study lies in evaluating the impact of varying protein intake levels (0.8 vs. 1.2 g/kg b.w/d) on muscle mass composition in elderly females suffering from sarcopenia. For this purpose, in this research trial, a total of 126 participants (60-75 years) were enrolled and equally divided into two groups: normal protein intake (0.8 g/kg b.w/d) and moderately high protein intake (1.2 g/kg b.w/d) for 12 weeks. The effects of dietary protein were assessed using anthropometric measurements, magnetic resonance imaging (MRI), handgrip, and knee flexion tests with baseline and post-intervention comparisons. Statistical analysis was conducted using SPSS, employing paired sample t-test at a significance level of p < 0.05. Results indicated a significant improvement in muscle mass composition with moderately high protein intake. Anthropometric parameters, including body mass (83.51 ± 4.23 kg) and waist circumference (113.90 ± 10.82 cm), showed notable enhancement in the moderately higher protein group. Muscle function and imaging assessments, such as handgrip strength and knee flexion, demonstrated improved functionality. MRI-derived measurements of the muscle composition of the calf (141.23 ± 4.87 MCSA, mm2 × 104) and thigh (258.04 ± 7.26 MCSA, mm2 × 104) further confirmed the positive impact of increased protein intake. The study concluded that a moderately high protein diet effectively supports muscle health in elderly females with sarcopenia. Therefore, an adequate protein intake may serve as a strategic nutritional intervention to mitigate muscle loss and improve overall physical function in aging women.

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来源期刊
Frontiers in Nutrition
Frontiers in Nutrition Agricultural and Biological Sciences-Food Science
CiteScore
5.20
自引率
8.00%
发文量
2891
审稿时长
12 weeks
期刊介绍: No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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