进食障碍住院治疗中的PTSD和复杂PTSD:对症状严重程度和结局轨迹的调节作用。

IF 4.3 2区 医学 Q1 NUTRITION & DIETETICS
Sinead Day, Deborah Mitchison, W. Kathy Tannous, Phillipa Hay
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引用次数: 0

摘要

目的:进食障碍(EDs)和创伤症状通常同时发生,但创伤如何影响ED治疗结果的研究有限。对于复杂的创伤后应激障碍(CPTSD)来说尤其如此。区分PTSD和CPTSD(包括PTSD症状和自组织紊乱[DSO])的治疗影响可能有助于ED医生解决这一常见的共病。方法:目前的研究包括95名患有EDs(主要是神经性厌食症)的女性(年龄= 26岁),她们接受了住院治疗(M = 81天)。参与者在入院、治疗第4周、出院和出院后6个月完成了ED症状、焦虑、抑郁、体重指数(BMI)、ED特异性健康相关生活质量(ED- hrqol)损害、功能残疾和创伤症状的测量。结果:除BMI外,所有结果在入院时和治疗第4周时伴有共病性创伤(基于可能的CPTSD或超过PTSD和DSO症状域的临床阈值)的个体更严重;然而,这些差异在出院时消失,在随访时仍然不显著。某些形式的共病性创伤减缓了焦虑、抑郁和残疾的结局轨迹(但不包括ED症状),因此,患有共病性创伤的个体在治疗早期改善较慢,在治疗后期改善较陡,出院后复发率较高。讨论:这些发现强调,PTSD和CPTSD症状域可能与住院治疗早期更严重的ED结果相关,这些结果在出院时得到解决,并可能预测次要结果的不同治疗反应。影响讨论临床评估和治疗共病创伤相关障碍在住院护理。试验注册:该研究于2021年11月在澳大利亚和新西兰临床试验注册中心前瞻性注册,注册号为ACTRN12621001651875。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

PTSD and Complex PTSD in Residential Treatment for Eating Disorders: Moderating Effects on Symptom Severity and Outcome Trajectory

PTSD and Complex PTSD in Residential Treatment for Eating Disorders: Moderating Effects on Symptom Severity and Outcome Trajectory

Objective

Eating disorders (EDs) and symptoms of trauma commonly co-occur, yet research is limited on how trauma affects ED treatment outcomes. This is particularly true for complex post-traumatic stress disorder (CPTSD). Differentiating between the treatment impacts of PTSD and CPTSD (which includes both PTSD symptoms and disturbances in self-organization [DSO]) may help ED providers address this common comorbidity.

Method

The current study included 95 women (M age = 26 years) with EDs (largely anorexia nervosa) who received residential treatment (M = 81 days). Participants completed measures of ED symptoms, anxiety, depression, body mass index (BMI), ED-specific health-related quality-of-life (ED-HRQoL) impairment, functional disability, and trauma symptoms at admission, week 4 of treatment, discharge, and 6 months post-discharge.

Results

All outcomes except BMI were more severe at admission and week 4 of treatment for individuals with comorbid trauma (based on probable CPTSD or exceeding the clinical threshold for PTSD and DSO symptom domains); however, these differences resolved by discharge and remained non-significant at follow-up. Some forms of comorbid trauma moderated outcome trajectories for anxiety, depression, and disability (but not ED symptoms), such that individuals with comorbid trauma showed slower improvement early in treatment, steeper improvement later in treatment, and greater resurgence after discharge.

Discussion

These findings highlight that PTSD and CPTSD symptom domains may be associated with more severe ED outcomes early in residential treatment that resolve by discharge, and may predict differential treatment response for secondary outcomes. Implications are discussed for clinical assessment and treatment of comorbid trauma-related disorders in residential care.

Trial Registration

The study was prospectively registered on the Australian and New Zealand Clinical Trials Registry in November 2021, registration number ACTRN12621001651875

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来源期刊
CiteScore
10.00
自引率
12.70%
发文量
204
审稿时长
4-8 weeks
期刊介绍: Articles featured in the journal describe state-of-the-art scientific research on theory, methodology, etiology, clinical practice, and policy related to eating disorders, as well as contributions that facilitate scholarly critique and discussion of science and practice in the field. Theoretical and empirical work on obesity or healthy eating falls within the journal’s scope inasmuch as it facilitates the advancement of efforts to describe and understand, prevent, or treat eating disorders. IJED welcomes submissions from all regions of the world and representing all levels of inquiry (including basic science, clinical trials, implementation research, and dissemination studies), and across a full range of scientific methods, disciplines, and approaches.
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