巴西传统饮食模式与代谢功能障碍相关的脂肪变性肝病患者晚期脂肪变性的风险较低相关

IF 3.4 3区 医学 Q2 NUTRITION & DIETETICS
Jéssica Silva Salarini , Lygia Nestal Barroso , Jade Veloso Freitas , Nathalie Carvalho Leite , Tatiana Pereira de Paula , Patrícia de Carvalho Padilha , Wilza Arantes Ferreira Peres
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引用次数: 0

摘要

确定代谢功能障碍相关脂肪变性肝病(MASLD)患者的饮食模式至关重要,因为营养是一个可改变的危险因素,有助于疾病的病因和进展。本研究评估了MASLD患者饮食模式与血脂和血糖谱、肝脏生物标志物、脂肪变性和纤维化程度之间的关系。在这项横断面研究中,70名完成了整个饮食评估的患者被纳入分析。通过24小时膳食回顾评估膳食摄入量,并通过探索性因子分析和主成分分析确定4种膳食模式。平均得分按性别、年龄组和营养状况进行分析,并通过二项logistic回归检验与主要结局的相关性,显著性设置为P >;. 05。男性更坚持谨慎的饮食模式(95% CI 2.1-2.84),包括新鲜水果和果汁、全谷物和面包、鸡蛋和鸡蛋制品、咖啡和茶,更坚持传统巴西饮食模式的人患晚期脂肪变性的几率更低(OR 0.46, 95% CI 0.20-0.97)。这种模式基于富含纤维、生物活性化合物和抗氧化剂的最低限度加工食品,被证明对晚期脂肪变性有保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Brazilian traditional dietary pattern was associated with a lower risk of advanced steatosis in patients with metabolic dysfunction-associated steatotic liver disease
Identifying dietary patterns in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) is critical, since nutrition is a modifiable risk factor that contributes to the etiology and progression of the disease. This study evaluated the association between dietary patterns and lipid and glycemic profiles, liver biomarkers, and degrees of steatosis and fibrosis in patients with MASLD. In this cross-sectional study, 70 patients who completed the entire dietary assessment were included in the analyses. Dietary intake was assessed through 24-hour dietary recalls, and 4 dietary patterns were identified by exploratory factor analysis and principal component analysis. Mean scores were analyzed by sex, age group, and nutritional status, and associations with main outcomes were tested by binomial logistic regression, with significance set at P > .05. There was greater adherence to the prudent pattern among men (95% CI 2.1-2.84), which consisted of fresh fruits and fruit juices, whole grains and breads, eggs and egg-based preparations, and coffee and tea, and a lower chance of advanced steatosis in individuals with greater adherence to the traditional Brazilian pattern (OR 0.46, 95% CI 0.20-0.97). This pattern, based on minimally processed foods rich in fiber, bioactive compounds, and antioxidants, was shown to be protective against advanced steatosis.
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来源期刊
Nutrition Research
Nutrition Research 医学-营养学
CiteScore
7.60
自引率
2.20%
发文量
107
审稿时长
58 days
期刊介绍: Nutrition Research publishes original research articles, communications, and reviews on basic and applied nutrition. The mission of Nutrition Research is to serve as the journal for global communication of nutrition and life sciences research on diet and health. The field of nutrition sciences includes, but is not limited to, the study of nutrients during growth, reproduction, aging, health, and disease. Articles covering basic and applied research on all aspects of nutrition sciences are encouraged, including: nutritional biochemistry and metabolism; metabolomics, nutrient gene interactions; nutrient requirements for health; nutrition and disease; digestion and absorption; nutritional anthropology; epidemiology; the influence of socioeconomic and cultural factors on nutrition of the individual and the community; the impact of nutrient intake on disease response and behavior; the consequences of nutritional deficiency on growth and development, endocrine and nervous systems, and immunity; nutrition and gut microbiota; food intolerance and allergy; nutrient drug interactions; nutrition and aging; nutrition and cancer; obesity; diabetes; and intervention programs.
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