位置细胞在中风后认知障碍中的位置。

IF 15.1 1区医学 Q1 NEUROSCIENCES

Trends in Neurosciences Pub Date : 2025-06-01 Epub Date: 2025-05-20 DOI:10.1016/j.tins.2025.05.001

Abbie C Chapman

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引用次数: 0

摘要

Heiser等人在最近的一项研究中发现，小鼠全脑微中风后，海马位置细胞稳定性和空间编码被破坏。这些发现表明，即使在没有局部病变的情况下，中风后海马神经元也特别容易受到功能障碍的影响。他们还强调了提高位置细胞稳定性和挽救中风后记忆功能的潜力。

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A place for place cells in post-stroke cognitive impairment.

In a recent study, Heiser et al. showed that hippocampal place cell stability and spatial encoding were disrupted in mice after brain-wide microstrokes. These findings suggest that hippocampal neurons are particularly vulnerable to dysfunction after stroke, even in the absence of local lesions. They also highlight the potential to improve place cell stability and rescue post-stroke memory function.

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来源期刊

Trends in Neurosciences 医学-神经科学

CiteScore

26.50

自引率

1.30%

发文量

123

审稿时长

6-12 weeks

期刊介绍： For over four decades, Trends in Neurosciences (TINS) has been a prominent source of inspiring reviews and commentaries across all disciplines of neuroscience. TINS is a monthly, peer-reviewed journal, and its articles are curated by the Editor and authored by leading researchers in their respective fields. The journal communicates exciting advances in brain research, serves as a voice for the global neuroscience community, and highlights the contribution of neuroscientific research to medicine and society.