儿童大疱性类天疱疮用Dupilumab治疗：一个病例报告良好的反应。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-05-22 DOI:10.1111/pde.15995

Aldana Belén Almassio, Laura Luna, Margarita Larralde

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引用次数: 0

摘要

大疱性类天疱疮（BP）是一种主要影响老年人的自身免疫性水疱疾病，在儿童中很少发生。我们报告一例3岁女孩BP谁最初失败的常规治疗，但获得完全缓解后杜匹单抗治疗。该病例表明，dupilumab可能是一种有效且安全的替代方案，用于治疗对标准疗法有耐药性的儿童BP，尽管需要进一步的研究来证实其有效性。

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Pediatric Bullous Pemphigoid Treated With Dupilumab: A Case Report With Good Response.

Bullous pemphigoid (BP) is an autoimmune blistering disorder predominantly affecting the elderly, with rare occurrences in children. We report a case of a 3-year-old girl with BP who initially failed conventional treatments but achieved complete remission following dupilumab therapy. This case suggests that dupilumab could be an effective and safe alternative for pediatric BP resistant to standard therapies, though further studies are needed to confirm its efficacy.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.