Fadime Daldaban, Jale Metin Kıyıcı, Bilal Akyüz, Esma Gamze Aksel, Mahmut Kaliber, Mehmet Ulaş Çınar, Korhan Arslan
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Association of the CACNA2D1 gene with milk yield and milk quality traits in Holstein cattle.
The aim of this study was to investigate the association of the rs43389227, rs43390124 and rs482883241 single-nucleotide polymorphisms (SNPs) of the bovine calcium channel, voltage-dependent, alpha-2/delta subunit 1 (CACNA2D1) gene with milk yield and quality traits in Holstein cattle. For this purpose, 166 Holstein dairy cows were genotyped for these three SNPs. Correlation analyses showed that the rs43389227 SNP was associated with 305-day milk yield (P < 0.05). Besides, rs43390124 SNP was found to be associated not only with 305-day milk yield but also with milk fat, milk quality traits, somatic cell score, electrical conductivity and pH (P < 0.05). The results of this study suggest that the rs43389227 and rs43390124 SNPs could be used in breeding for the improvement of milk yield and milk quality in cattle. Furthermore, based on its association with mastitis related traits, the rs43390124 SNP was considered as a potential indicator of mastitis susceptibility.
期刊介绍：
The Journal of Dairy Research is an international Journal of high-standing that publishes original scientific research on all aspects of the biology, wellbeing and technology of lactating animals and the foods they produce. The Journal’s ability to cover the entire dairy foods chain is a major strength. Cross-disciplinary research is particularly welcomed, as is comparative lactation research in different dairy and non-dairy species and research dealing with consumer health aspects of dairy products. Journal of Dairy Research: an international Journal of the lactation sciences.
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