近红外半导体激光辐照生物皮肤组织的非致死激光热色散研究

IF 4.6 2区 物理与天体物理 Q1 OPTICS
Rui Zhang , Zhenfu Wang , Xiaohui Li , Te Li , Fang Peng , Junyue Zhang , Jiachen Liu , Shunhua Wu , Weizhou Huang , Xiwei Huang , Lei Ling , Qingkai Meng , Lang Chen , Jiachen Zhang
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引用次数: 0

摘要

非致命激光由于其多样化的功能,在军事和生物医学应用中引起了相当大的兴趣,其中热色散是一个突出的应用。然而,对非致死性热色散激光与生物组织之间相互作用机制的研究仍然有限。本研究建立了代表皮肤生物结构的四层组织模型,并分析了不同激光束对皮肤组织的热效应。利用修正的比尔-朗伯定律和阿伦尼乌斯方程确定了激光辐照下的色散和损伤阈值。通过仿真和实验验证,测得976 nm激光的热扩散阈值为9.18 W/cm2。本文从光源、热源、血液灌注、多层组织模型等方面对激光照射下皮肤组织温度的动态平衡现象进行了深入的解释。这项工作阐明了激光在生物皮肤组织中诱导热扩散的基本机制,为激光热扩散技术的未来发展提供了有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Study of near-infrared semiconductor laser irradiation of biological skin tissues for non-lethal laser thermal dispersion
Non-lethal lasers have attracted considerable interest in both military and biomedical applications owing to their diverse range of functionalities, with thermal dispersion being one prominent application. However, investigations into the interaction mechanisms between non-lethal thermal dispersive lasers and biological tissues remain limited. In this study, a four-layer tissue model representing the biological structure of skin is developed, and the thermal effects of different laser beams on skin tissues are analysed. The dispersion and damage thresholds under laser irradiation are determined using the modified Beer-Lambert law and the Arrhenius equation. Validation through simulation and experimentation, the thermal dispersal threshold of 976 nm laser is measured to be 9.18 W/cm2. The paper provides an in-depth explanation of the dynamic equilibrium phenomenon in skin tissue temperature under laser irradiation, incorporating the light source, heat source, blood perfusion, and the multilayer tissue model. This work elucidates the fundamental mechanisms of laser-induced heat diffusion in biological skin tissues, offering valuable insights for the future development of laser-based heat diffusion technologies.
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来源期刊
CiteScore
8.50
自引率
10.00%
发文量
1060
审稿时长
3.4 months
期刊介绍: Optics & Laser Technology aims to provide a vehicle for the publication of a broad range of high quality research and review papers in those fields of scientific and engineering research appertaining to the development and application of the technology of optics and lasers. Papers describing original work in these areas are submitted to rigorous refereeing prior to acceptance for publication. The scope of Optics & Laser Technology encompasses, but is not restricted to, the following areas: •development in all types of lasers •developments in optoelectronic devices and photonics •developments in new photonics and optical concepts •developments in conventional optics, optical instruments and components •techniques of optical metrology, including interferometry and optical fibre sensors •LIDAR and other non-contact optical measurement techniques, including optical methods in heat and fluid flow •applications of lasers to materials processing, optical NDT display (including holography) and optical communication •research and development in the field of laser safety including studies of hazards resulting from the applications of lasers (laser safety, hazards of laser fume) •developments in optical computing and optical information processing •developments in new optical materials •developments in new optical characterization methods and techniques •developments in quantum optics •developments in light assisted micro and nanofabrication methods and techniques •developments in nanophotonics and biophotonics •developments in imaging processing and systems
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