Clinical effectiveness of 3D SPECT/CT imaging in determining osteotomy range for surgical treatment of medication-related osteonecrosis of the jaw: a retrospective study

Objective

This study aims to evaluate the clinical effectiveness of 3D SPECT/CT imaging in determining the osteotomy range during surgical treatment of Medication-Related Osteonecrosis of the Jaw (MRONJ) when combined with composite tissue flap techniques.

Methods

A retrospective analysis was conducted involving 12 patients diagnosed with MRONJ. Each patient underwent a 3D SPECT/CT examination prior to surgery, where the region of interest (ROI) was outlined in the 3D images. During surgery, the affected bone was excised 0.5 cm beyond the delineated ROI. Various types of composite tissue flaps were utilized to close the defects based on their size and location.

Results

Patients were followed for an average of 7.9 months (range: 6–12 months), with all 12 achieving successful outcomes devoid of complications such as pyorrhea.

Conclusion

The utilization of 3D SPECT/CT enhances the precision of determining the osteotomy range in MRONJ surgeries. Coupled with composite tissue flap techniques for defect closure, this approach yields favorable clinical outcomes.