三维SPECT/CT成像在确定药物相关性颌骨骨坏死手术治疗截骨范围中的临床效果：一项回顾性研究

IF 2.2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-04-15 DOI:10.1016/j.jormas.2025.102375

Yubo Wei, Dongpo Li, Meng Wang, Congcong Wang, Xinfeng Liu, Yingying Zhang, Shuangyi Wang, Guoliang Li

{"title":"三维SPECT/CT成像在确定药物相关性颌骨骨坏死手术治疗截骨范围中的临床效果：一项回顾性研究","authors":"Yubo Wei, Dongpo Li, Meng Wang, Congcong Wang, Xinfeng Liu, Yingying Zhang, Shuangyi Wang, Guoliang Li","doi":"10.1016/j.jormas.2025.102375","DOIUrl":null,"url":null,"abstract":"Objective: This study aims to evaluate the clinical effectiveness of 3D SPECT/CT imaging in determining the osteotomy range during surgical treatment of Medication-Related Osteonecrosis of the Jaw (MRONJ) when combined with composite tissue flap techniques.Methods: A retrospective analysis was conducted involving 12 patients diagnosed with MRONJ. Each patient underwent a 3D SPECT/CT examination prior to surgery, where the region of interest (ROI) was outlined in the 3D images. During surgery, the affected bone was excised 0.5 cm beyond the delineated ROI. Various types of composite tissue flaps were utilized to close the defects based on their size and location.Results: Patients were followed for an average of 7.9 months (range: 6-12 months), with all 12 achieving successful outcomes devoid of complications such as pyorrhea.Conclusion: The utilization of 3D SPECT/CT enhances the precision of determining the osteotomy range in MRONJ surgeries. Coupled with composite tissue flap techniques for defect closure, this approach yields favorable clinical outcomes.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102375"},"PeriodicalIF":2.2000,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical effectiveness of 3D SPECT/CT imaging in determining osteotomy range for surgical treatment of medication-related osteonecrosis of the jaw: a retrospective study.\",\"authors\":\"Yubo Wei, Dongpo Li, Meng Wang, Congcong Wang, Xinfeng Liu, Yingying Zhang, Shuangyi Wang, Guoliang Li\",\"doi\":\"10.1016/j.jormas.2025.102375\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: This study aims to evaluate the clinical effectiveness of 3D SPECT/CT imaging in determining the osteotomy range during surgical treatment of Medication-Related Osteonecrosis of the Jaw (MRONJ) when combined with composite tissue flap techniques.Methods: A retrospective analysis was conducted involving 12 patients diagnosed with MRONJ. Each patient underwent a 3D SPECT/CT examination prior to surgery, where the region of interest (ROI) was outlined in the 3D images. During surgery, the affected bone was excised 0.5 cm beyond the delineated ROI. Various types of composite tissue flaps were utilized to close the defects based on their size and location.Results: Patients were followed for an average of 7.9 months (range: 6-12 months), with all 12 achieving successful outcomes devoid of complications such as pyorrhea.Conclusion: The utilization of 3D SPECT/CT enhances the precision of determining the osteotomy range in MRONJ surgeries. Coupled with composite tissue flap techniques for defect closure, this approach yields favorable clinical outcomes.\",\"PeriodicalId\":56038,\"journal\":{\"name\":\"Journal of Stomatology Oral and Maxillofacial Surgery\",\"volume\":\" \",\"pages\":\"102375\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Stomatology Oral and Maxillofacial Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jormas.2025.102375\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Stomatology Oral and Maxillofacial Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jormas.2025.102375","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Dentistry","Score":null,"Total":0}

引用次数: 0

摘要

目的：本研究旨在评价三维SPECT/CT成像结合复合组织瓣技术在药物相关性颌骨坏死（MRONJ）手术治疗中确定截骨范围的临床效果。方法：对12例诊断为MRONJ的患者进行回顾性分析。每位患者在手术前接受3D SPECT/CT检查，其中感兴趣区域（ROI）在3D图像中勾画。在手术中，受影响的骨在划定的ROI外0.5 cm处切除。根据缺损的大小和位置，采用不同类型的复合组织瓣来闭合缺损。结果：患者平均随访7.9个月（范围：6-12个月），所有12例患者均获得成功，无脓漏等并发症。结论：三维SPECT/CT的应用提高了MRONJ手术截骨范围的确定精度。结合复合组织瓣技术修复缺损，该方法可获得良好的临床效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Clinical effectiveness of 3D SPECT/CT imaging in determining osteotomy range for surgical treatment of medication-related osteonecrosis of the jaw: a retrospective study.

Objective: This study aims to evaluate the clinical effectiveness of 3D SPECT/CT imaging in determining the osteotomy range during surgical treatment of Medication-Related Osteonecrosis of the Jaw (MRONJ) when combined with composite tissue flap techniques.

Methods: A retrospective analysis was conducted involving 12 patients diagnosed with MRONJ. Each patient underwent a 3D SPECT/CT examination prior to surgery, where the region of interest (ROI) was outlined in the 3D images. During surgery, the affected bone was excised 0.5 cm beyond the delineated ROI. Various types of composite tissue flaps were utilized to close the defects based on their size and location.

Results: Patients were followed for an average of 7.9 months (range: 6-12 months), with all 12 achieving successful outcomes devoid of complications such as pyorrhea.

Conclusion: The utilization of 3D SPECT/CT enhances the precision of determining the osteotomy range in MRONJ surgeries. Coupled with composite tissue flap techniques for defect closure, this approach yields favorable clinical outcomes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Stomatology Oral and Maxillofacial Surgery Dentistry-Oral Surgery

CiteScore

2.20

自引率

9.10%

发文量

305

期刊介绍： J Stomatol Oral Maxillofac Surg publishes research papers and techniques - (guest) editorials, original articles, reviews, technical notes, case reports, images, letters to the editor, guidelines - dedicated to enhancing surgical expertise in all fields relevant to oral and maxillofacial surgery: from plastic and reconstructive surgery of the face, oral surgery and medicine, … to dentofacial and maxillofacial orthopedics. Original articles include clinical or laboratory investigations and clinical or equipment reports. Reviews include narrative reviews, systematic reviews and meta-analyses. All manuscripts submitted to the journal are subjected to peer review by international experts, and must: Be written in excellent English, clear and easy to understand, precise and concise; Bring new, interesting, valid information - and improve clinical care or guide future research; Be solely the work of the author(s) stated; Not have been previously published elsewhere and not be under consideration by another journal; Be in accordance with the journal''s Guide for Authors'' instructions: manuscripts that fail to comply with these rules may be returned to the authors without being reviewed. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey Platforms.