{"title":"关于高效氯氰菊酯最大限量和筛选现有欧盟氯氰菊酯最大限量的声明","authors":"European Food Safety Authority (EFSA)","doi":"10.2903/j.efsa.2025.9386","DOIUrl":null,"url":null,"abstract":"<p>In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to prepare a statement on the maximum residue level (MRL) proposals for alpha-cypermethrin and to perform a screening of the existing MRLs for cypermethrins based on the toxicological reference values of alpha-cypermethrin. Conversion factors based on the isomeric composition in the technical mixtures and commercial formulations of alpha-cypermethrin, zeta-cypermethrins and cypermethrins (sum of isomers) were used to recalculate MRL values proposed in the 2023 MRL review (and based on existing EU uses, import tolerances or codex maximum residue limits for cypermethrin and zeta-cypermethrin) into alpha-cypermethrin. The combined risk assessment conducted in the MRL review is expected to cover the MRLs calculated as alpha-cypermethrin in the present assessment. Moreover, a screening of the existing EU MRLs for cypermethrins considering the toxicological reference values of the more toxic alpha-cypermethrin was carried out. Two lists of MRLs, list MRL 1 expressing the residue as cypermethrin including other mixtures of constituent isomers (sum of isomers) and list MRL 2 expressing the residue as alpha-cypermethrin, are presented for further consideration by risk managers.</p>","PeriodicalId":11657,"journal":{"name":"EFSA Journal","volume":"23 4","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2025.9386","citationCount":"0","resultStr":"{\"title\":\"Statement on MRLs for alpha-cypermethrin and screening of the existing EU MRLs for cypermethrin\",\"authors\":\"European Food Safety Authority (EFSA)\",\"doi\":\"10.2903/j.efsa.2025.9386\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to prepare a statement on the maximum residue level (MRL) proposals for alpha-cypermethrin and to perform a screening of the existing MRLs for cypermethrins based on the toxicological reference values of alpha-cypermethrin. Conversion factors based on the isomeric composition in the technical mixtures and commercial formulations of alpha-cypermethrin, zeta-cypermethrins and cypermethrins (sum of isomers) were used to recalculate MRL values proposed in the 2023 MRL review (and based on existing EU uses, import tolerances or codex maximum residue limits for cypermethrin and zeta-cypermethrin) into alpha-cypermethrin. The combined risk assessment conducted in the MRL review is expected to cover the MRLs calculated as alpha-cypermethrin in the present assessment. Moreover, a screening of the existing EU MRLs for cypermethrins considering the toxicological reference values of the more toxic alpha-cypermethrin was carried out. Two lists of MRLs, list MRL 1 expressing the residue as cypermethrin including other mixtures of constituent isomers (sum of isomers) and list MRL 2 expressing the residue as alpha-cypermethrin, are presented for further consideration by risk managers.</p>\",\"PeriodicalId\":11657,\"journal\":{\"name\":\"EFSA Journal\",\"volume\":\"23 4\",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2025.9386\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EFSA Journal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9386\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EFSA Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9386","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
根据法规(EC) No 396/2005第43条,欧盟委员会要求欧洲食品安全局准备一份关于高效氯氰菊酯最大残留限量(MRL)提案的声明,并根据高效氯氰菊酯的毒理学参考值对现有的高效氯氰菊酯最大残留限量进行筛选。采用基于高效氯氰菊酯、高效氯氰菊酯和高效氯氰菊酯的技术混合物和商业配方中的异构体组成的转换因子(异构体的总和)重新计算2023年MRL审查中提出的MRL值(并基于现有的欧盟用途、进口容许量或高效氯氰菊酯和高效氯氰菊酯的法典最大残留限量)。在最大残留限量审查中进行的综合风险评估预计将涵盖本评估中计算为高效氯氰菊酯的最大残留限量。此外,考虑到毒性更强的α -氯氰菊酯的毒理学参考值,对现有的欧盟氯氰菊酯最大残留限量进行了筛选。提出了两份最大残留限量清单,其中一份MRL 1表示残留为氯氰菊酯,包括其他组分异构体的混合物(异构体的总和),另一份MRL 2表示残留为α -氯氰菊酯,供风险管理人员进一步考虑。
Statement on MRLs for alpha-cypermethrin and screening of the existing EU MRLs for cypermethrin
In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to prepare a statement on the maximum residue level (MRL) proposals for alpha-cypermethrin and to perform a screening of the existing MRLs for cypermethrins based on the toxicological reference values of alpha-cypermethrin. Conversion factors based on the isomeric composition in the technical mixtures and commercial formulations of alpha-cypermethrin, zeta-cypermethrins and cypermethrins (sum of isomers) were used to recalculate MRL values proposed in the 2023 MRL review (and based on existing EU uses, import tolerances or codex maximum residue limits for cypermethrin and zeta-cypermethrin) into alpha-cypermethrin. The combined risk assessment conducted in the MRL review is expected to cover the MRLs calculated as alpha-cypermethrin in the present assessment. Moreover, a screening of the existing EU MRLs for cypermethrins considering the toxicological reference values of the more toxic alpha-cypermethrin was carried out. Two lists of MRLs, list MRL 1 expressing the residue as cypermethrin including other mixtures of constituent isomers (sum of isomers) and list MRL 2 expressing the residue as alpha-cypermethrin, are presented for further consideration by risk managers.
期刊介绍:
The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.