缺血性脑卒中后癫痫动物模型的建立

IF 2.9 3区医学 Q2 NEUROSCIENCES

Neuroscience Pub Date : 2025-04-18 DOI:10.1016/j.neuroscience.2025.04.029

Min He , Donghui Wang , Kunling Yang, Hengchang Qi, Chaoning Liu, Lanfeng Sun, Lei Wei, Yuan Wu

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引用次数: 0

摘要

中风是全球致残和死亡的主要原因之一，其中缺血性中风（IS）是最常见的亚型。卒中后癫痫（PSE）是卒中后一种重要且常见的并发症，给患者、其家庭和整个社会带来了沉重的负担。建立可靠的动物模型对于探讨PSE的发病机制和治疗方法至关重要。本文综述了缺血性脑卒中后癫痫动物模型的研究进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Animal models of epilepsy after ischemic stroke

Stroke ranks among the foremost causes of disability and mortality globally, with ischemic stroke (IS) being the most prevalent subtype. Post-stroke epilepsy (PSE) represents a significant and common complication following a stroke, imposing substantial burdens on patients, their families, and society at large. Establishing a reliable animal model is crucial for investigating the mechanisms and potential treatments for PSE. This article offers a review of studies pertaining to animal models of epilepsy subsequent to ischemic stroke.

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来源期刊

Neuroscience 医学-神经科学

CiteScore

6.20

自引率

0.00%

发文量

394

审稿时长

52 days

期刊介绍： Neuroscience publishes papers describing the results of original research on any aspect of the scientific study of the nervous system. Any paper, however short, will be considered for publication provided that it reports significant, new and carefully confirmed findings with full experimental details.