饲料添加剂反式茴香醚和丁香酚在所有禽类中使用的安全性和有效性(ADISSEO、ADM、AGOLIN(爱尔兰)有限公司、嘉吉、帝斯曼营养产品有限公司、LABORATORIES PHODE、Norel S.A.)

IF 3.3 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Maria de Lourdes Bastos, Paul Brantom, Andrew Chesson, Josef Schlatter, Johannes Westendorf, Maria Dulak-Lis, Paola Manini
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引用次数: 0

摘要

应欧盟委员会的请求,欧洲食品安全局被要求就 1-甲氧基-4-(丙-1-(反式)-烯基)苯(反式-乙烯基)和丁香酚作为感官饲料添加剂用于所有禽类物种的安全性和有效性发表科学意见。这些添加剂已获准用于除鱼类和家禽以外的所有动物物种。评估中的添加剂--反式乙醚(化学合成或天然来源)和天然来源的丁香酚,被认为对育肥动物(鸡和火鸡)没有安全问题,而且在建议的最高使用量(25 毫克/千克全价饲料)范围内,对长寿和繁殖动物(蛋鸡)也不太可能产生不良影响。这些结论可推断出与生理相关的次要物种。在饲料中使用反式乙内酰脲和丁香酚的最高建议使用量不会对动物产品的消费者造成安全问题。使用反式乙内酰脲和丁香酚作为饲料添加剂对环境是安全的。关于使用者的安全性,反式茴香硫醚对皮肤和眼睛没有刺激性,但会引起皮肤过敏。丁香酚对皮肤和眼睛有刺激性,会引起皮肤过敏。在处理反式茴香醚或丁香酚时,未采取防护措施的使用者可能会接触到雌烯醚或甲基丁香酚。因此,为降低风险,应尽量减少使用者的接触。由于反式茴香醚和丁香酚在食品中用作香料,而它们在饲料中的作用与在食品中的作用基本相同,因此无需进一步证明其功效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Safety and efficacy of the feed additives trans-anethole and eugenol for use in all avian species (ADISSEO, ADM, AGOLIN (Ireland) Ltd, Cargill, DSM Nutritional Products Ltd., LABORATORIES PHODE, Norel S.A.)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 1-methoxy-4-(prop-1-(trans)-enyl)benzene (trans-anethole) and eugenol as sensory feed additives for all avian species. The additives are already authorised for use in all animal species except fish and poultry. The additives under assessment, trans-anethole (from either chemical synthesis or natural origin) and eugenol of natural origin, are considered of no safety concern for species (chickens and turkeys) for fattening and of being very unlikely to induce adverse effects in long-living and reproductive animals (laying hens) up to the maximum proposed use levels of 25 mg/kg complete feed. These conclusions are extrapolated to physiologically-related minor species. No safety concern would be expected for the consumer of animal products from the use of trans-anethole and eugenol up to the maximum proposed use level in feed. The use of trans-anethole and eugenol as feed additives is considered safe for the environment. Regarding user safety, trans-anethole is not irritant to skin and eyes but is a dermal sensitiser. Eugenol is irritant to skin and eyes and is a dermal sensitiser. When handling trans-anethole or eugenol, exposure of unprotected users to estragole or methyleugenol may occur. Therefore, to reduce the risk, the exposure of the users should be minimised. Since trans-anethole and eugenol are used in food as flavourings, and their function in feed is essentially the same as that in food, no further demonstration of efficacy is necessary.

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来源期刊
EFSA Journal
EFSA Journal Veterinary-Veterinary (miscellaneous)
CiteScore
5.20
自引率
21.20%
发文量
422
审稿时长
5 weeks
期刊介绍: The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.
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