青少年体感诱发电位的变化特征

IF 2 Q3 NEUROSCIENCES

Clinical Neurophysiology Practice Pub Date : 2025-01-01 DOI:10.1016/j.cnp.2025.03.004

Aoi Mase , Manabu Shibasaki , Hiroki Nakata

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引用次数: 0

摘要

目的通过对儿童、青年、男性和女性的比较，研究青少年体感加工的变化特征，特别是性别差异。方法调查对象包括26名小学生（ESC）、36名青少年（ADO）和36名大学生（CS）。我们用电刺激右正中神经记录体感诱发电位（SEPs）。在Fz处测量P12、N15、P18和N30的峰值潜伏期和振幅，在C3 '处测量P12 （P1）、N18 （N1）、P22 （P2）、N27 （N2）、P3、N3、P45 （P4）和N60 （N4）的峰值潜伏期和振幅。结果C3′处P22 （P2）振幅随年龄增大而减小。Fz点N15波幅在各组中均较大。P3和N3在C3 '的发生率随着年龄的增长而下降，但在ADO中与CS相比仍然很高。相关分析显示，ADO男孩C3′处P22 （P2）振幅与年龄呈显著负相关，而ADO女孩、ESC男孩和ESC女孩无显著负相关。结论ADO的体感加工不如CS成熟，且存在性别差异。我们的发现可能有助于理解发育障碍儿童的神经活动，支持基于感觉的治疗。

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Changing characteristics of somatosensory evoked potentials in adolescents

Objective

We investigated changing characteristics of somatosensory processing in adolescents, particularly sex differences, by comparing children, young adults, and males and females.

Methods

Participants included 26 elementary school children (ESC), 36 adolescents (ADO), and 36 college students (CS). We recorded somatosensory evoked potentials (SEPs) using electrical stimulation of the right median nerve. Peak latencies and amplitudes were measured for P12, N15, P18, and N30 at Fz, and for P12 (P1), N18 (N1), P22 (P2), N27 (N2), P3, N3, P45 (P4), and N60 (N4) at C3′.

Results

The P22 (P2) amplitude at C3′ decreased with age. The N15 amplitude at Fz was larger in females across all groups. P3 and N3 occurrence at C3′ decreased with age but remained high in ADO compared to CS. Correlation analysis showed a significant negative correlation between P22 (P2) amplitude at C3′ and age in ADO boys, but not in ADO girls, ESC boys, or ESC girls.

Conclusions

Somatosensory processing in ADO is not as mature as in CS, with sex differences between ADO boys and girls.

Significance

Our findings may aid understanding of neural activity in children with developmental disorders, supporting sensory-based therapies.

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来源期刊

Clinical Neurophysiology Practice NEUROSCIENCES-

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.