EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Luca Tosti, Ruud Woutersen, Jaume Galobart, Maria Vittoria Vettori, Angelica Amaduzzi, Maria Dulak-Lis, Laura Iancu, Fabiola Pizzo, Eleni Gkimprixi
{"title":"所有动物品种的饲料添加剂盐酸硫胺素（3a820）和单硝酸硫胺素（3a821）（维生素B1）授权更新评估（帝斯曼营养产品有限公司和欧法添加剂有限公司）","authors":"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Luca Tosti, Ruud Woutersen, Jaume Galobart, Maria Vittoria Vettori, Angelica Amaduzzi, Maria Dulak-Lis, Laura Iancu, Fabiola Pizzo, Eleni Gkimprixi","doi":"10.2903/j.efsa.2025.9347","DOIUrl":null,"url":null,"abstract":"<p>Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin B<sub>1</sub> (thiamine hydrochloride and thiamine mononitrate) for the renewal of its authorisation as nutritional feed additive for all animal species. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that vitamin B<sub>1</sub> remains safe for all animal species, consumers and the environment. Thiamine mononitrate is not irritant to the eyes, while hydrochloride is not irritant to skin, but it is irritant to the eyes. Both salts of thiamine are considered skin and respiratory sensitisers, and any exposure is considered a risk. These conclusions would apply, in principle, to any preparations produced with the thiamine mononitrate. The Panel concluded there is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.</p>","PeriodicalId":11657,"journal":{"name":"EFSA Journal","volume":"23 4","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2025.9347","citationCount":"0","resultStr":"{\"title\":\"Assessment of the feed additives thiamine hydrochloride (3a820) and thiamine mononitrate (3a821) (vitamin B1) for all animal species for the renewal of their authorisation (DSM Nutritional Products Ltd. and Orffa Additives BV)\",\"authors\":\"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Luca Tosti, Ruud Woutersen, Jaume Galobart, Maria Vittoria Vettori, Angelica Amaduzzi, Maria Dulak-Lis, Laura Iancu, Fabiola Pizzo, Eleni Gkimprixi\",\"doi\":\"10.2903/j.efsa.2025.9347\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin B<sub>1</sub> (thiamine hydrochloride and thiamine mononitrate) for the renewal of its authorisation as nutritional feed additive for all animal species. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that vitamin B<sub>1</sub> remains safe for all animal species, consumers and the environment. Thiamine mononitrate is not irritant to the eyes, while hydrochloride is not irritant to skin, but it is irritant to the eyes. Both salts of thiamine are considered skin and respiratory sensitisers, and any exposure is considered a risk. These conclusions would apply, in principle, to any preparations produced with the thiamine mononitrate. The Panel concluded there is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.</p>\",\"PeriodicalId\":11657,\"journal\":{\"name\":\"EFSA Journal\",\"volume\":\"23 4\",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-04-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2025.9347\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EFSA Journal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9347\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EFSA Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9347","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Assessment of the feed additives thiamine hydrochloride (3a820) and thiamine mononitrate (3a821) (vitamin B1) for all animal species for the renewal of their authorisation (DSM Nutritional Products Ltd. and Orffa Additives BV)
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of vitamin B1 (thiamine hydrochloride and thiamine mononitrate) for the renewal of its authorisation as nutritional feed additive for all animal species. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that vitamin B1 remains safe for all animal species, consumers and the environment. Thiamine mononitrate is not irritant to the eyes, while hydrochloride is not irritant to skin, but it is irritant to the eyes. Both salts of thiamine are considered skin and respiratory sensitisers, and any exposure is considered a risk. These conclusions would apply, in principle, to any preparations produced with the thiamine mononitrate. The Panel concluded there is no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.
期刊介绍：
The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.
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