尿中医院源性朝日毛磷的临床意义：一项回顾性队列研究。

IF 2.2 4区医学 Q2 INFECTIOUS DISEASES

Infectious diseases now Pub Date : 2025-03-25 DOI:10.1016/j.idnow.2025.105059

Bruno Ali Lopez Luis, Karla alhelí León-Palacios, Araceli Acosta-Ruiz, Ana Maria Gonzalez-Cardel, Graciela Rodriguez-Zuñiga

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引用次数: 0

摘要

目的：探讨院内获得性尿培养阳性的Trichosporon sp患者的临床特点和预后。方法：2019-2023年回顾性队列研究，纳入尿中分离出三磷菌的所有患者；他们的临床数据和结果来自医疗记录。结果：26例患者出现尿朝日赤丝病。用朝日肠杆菌进行尿培养前的住院时间平均为25 天。70%的人留在了重症监护室。所有患者都有额外的细菌感染，并正在接受抗生素治疗。在最初的30 天里，只有57 %存活。没有与死亡率显著相关的因素。结论：在延长住院时间的患者尿液培养中分离出朝日肠杆菌，不提示有侵袭性疾病。尿中有朝日肠杆菌可能是危重病人死亡风险高的标志。

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Clinical significance of nosocomial Trichosporon asahii in urine: A retrospective cohort study

Objectives

To describe the clinical characteristics and outcomes of patients with urine cultures positive for Trichosporon sp with nosocomial acquisition.

Methods

Retrospective cohort study between 2019 and 2023 that included all patients with urinary isolates of Trichosporon sp; their clinical data and outcomes were drawn from medical records.

Results

Twenty-six patients had urinary Trichosporon asahii. Length of hospital stay before urinary culture with T. asahii averaged 25 days. Seventy percent stayed in the intensive care unit. All patients had an additional bacterial infection and were receiving antibiotic therapy. During the first 30 days, only 57 % were alive. There were no factors significantly associated with mortality.

Conclusions

The isolation of T. asahii in urine cultures of patients with extended hospital stay does not suggest invasive disease. T. asahii in urine may be a marker of critically ill patients with a high risk of mortality.

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