肠外纳米载体和给药装置的研究进展综述。

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Devesh U Kapoor, Bhupendra G Prajapati, Sankha Bhattacharya, Nidhi Jain Singhai, Rahul Maheshwari
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引用次数: 0

摘要

随着纳米载体和先进的肠外给药装置的出现,药物递送领域取得了重大进展。纳米载体是药物传递中的一个重要话题,本文介绍了它们的重要性和不同的应用,并对常规注射剂和肠外纳米载体进行了比较,重点分析了它们的局限性,并提出了创新的解决方案,以提高它们的功效和稳定性。随后的讨论深入到先进的肠外纳米载体,包括固体脂质纳米颗粒、脂质体、聚合物纳米颗粒、金属纳米颗粒、树状大分子、碳纳米管和石墨烯。每一种纳米颗粒类型都是根据其独特的性质、研究进展和在肠外给药中的潜在应用来评估的。此外,探讨了先进的无菌给药装置,强调了其在提高肠外给药的准确性和有效性方面的作用。全面的市场分析提供了当前趋势的见解,主要参与者,和未来前景的注射纳米载体。最后,讨论了监管方面的观点,重点讨论了批准和监管肠外纳米载体的挑战和考虑因素。本文最后总结了这一快速发展的肠外纳米载体领域的主要发现及其对未来研究和发展的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances in Parenteral Nanocarriers and Delivery Devices: A Comprehensive Review.

The field of drug delivery has witnessed significant advancements with the emergence of nanocarriers and advanced delivery devices for parenteral administration. Nanocarriers, a prominent topic in drug delivery, are introduced with an emphasis on their significance and diverse applications A critical analysis compares conventional injectables with parenteral nanocarriers, focusing on identifying limitations and proposing innovative solutions to enhance their efficacy and stability. The subsequent discussion delves into advanced parenteral nanocarriers, including solid lipid nanoparticles, liposomes, polymeric nanoparticles, metallic nanoparticles, dendrimers, carbon nanotubes, and graphene. Each nanoparticle type is assessed based on its unique properties, advancements in research, and potential applications in parenteral drug delivery. Furthermore, advanced sterile drug delivery devices are explored, highlighting their role in enhancing precision and efficacy in parenteral administration. A comprehensive market analysis provides insights into current trends, key players, and future prospects in parenteral nanocarriers. Lastly, regulatory perspectives are discussed, focusing on the challenges and considerations in approving and regulating parenteral nanocarriers. The paper concludes with a summary of key findings and implications for future research and development in this rapidly evolving field of parenteral nanocarriers.

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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
302
审稿时长
2 months
期刊介绍: Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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