Pengfei Wang , Minggui Gong , Rui Zhao , Zhaozhou Li , Huaibin Kang , Ying Hou , Wenfen Zhang , Huawei Niu , Shusheng Zhang
{"title":"环境和食品样品中甲醛小分子荧光探针检测研究进展综述","authors":"Pengfei Wang , Minggui Gong , Rui Zhao , Zhaozhou Li , Huaibin Kang , Ying Hou , Wenfen Zhang , Huawei Niu , Shusheng Zhang","doi":"10.1016/j.foodchem.2025.144041","DOIUrl":null,"url":null,"abstract":"<div><div>Formaldehyde (FA), a hazardous substance with carcinogenicity and mutagenicity, necessitates sensitive and accurate detection methods for protecting public health and the environment. While numerous reviews have explored FA fluorescent probes, the current literature predominantly emphasizes biological systems, leaving a gap in addressing FA’s roles in environmental monitoring and food safety. This review discusses recognition mechanisms for FA detection, including 2-aza-Cope rearrangement, methylenehydrazine reaction, formimine formation, and other mechanisms. Furthermore, this review underscores the practical applications of these probes in real-world contexts, namely their incorporation into test strips, hydrogels, and membranes for environmental monitoring and food safety. Moreover, this review highlights future directions for developing intelligent detection systems that combine fluorescent probes with data processing algorithms and artificial intelligence technologies. By synthesizing the current knowledge in this area, this review aims to stimulate future research and advancements in FA detection technology, ultimately contributing to improved environmental management and public health protection.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"481 ","pages":"Article 144041"},"PeriodicalIF":9.8000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Advancements in small molecule fluorescent probes for the detection of formaldehyde in environmental and food samples: A comprehensive review\",\"authors\":\"Pengfei Wang , Minggui Gong , Rui Zhao , Zhaozhou Li , Huaibin Kang , Ying Hou , Wenfen Zhang , Huawei Niu , Shusheng Zhang\",\"doi\":\"10.1016/j.foodchem.2025.144041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Formaldehyde (FA), a hazardous substance with carcinogenicity and mutagenicity, necessitates sensitive and accurate detection methods for protecting public health and the environment. While numerous reviews have explored FA fluorescent probes, the current literature predominantly emphasizes biological systems, leaving a gap in addressing FA’s roles in environmental monitoring and food safety. This review discusses recognition mechanisms for FA detection, including 2-aza-Cope rearrangement, methylenehydrazine reaction, formimine formation, and other mechanisms. Furthermore, this review underscores the practical applications of these probes in real-world contexts, namely their incorporation into test strips, hydrogels, and membranes for environmental monitoring and food safety. Moreover, this review highlights future directions for developing intelligent detection systems that combine fluorescent probes with data processing algorithms and artificial intelligence technologies. By synthesizing the current knowledge in this area, this review aims to stimulate future research and advancements in FA detection technology, ultimately contributing to improved environmental management and public health protection.</div></div>\",\"PeriodicalId\":318,\"journal\":{\"name\":\"Food Chemistry\",\"volume\":\"481 \",\"pages\":\"Article 144041\"},\"PeriodicalIF\":9.8000,\"publicationDate\":\"2025-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Chemistry\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0308814625012920\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0308814625012920","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Advancements in small molecule fluorescent probes for the detection of formaldehyde in environmental and food samples: A comprehensive review
Formaldehyde (FA), a hazardous substance with carcinogenicity and mutagenicity, necessitates sensitive and accurate detection methods for protecting public health and the environment. While numerous reviews have explored FA fluorescent probes, the current literature predominantly emphasizes biological systems, leaving a gap in addressing FA’s roles in environmental monitoring and food safety. This review discusses recognition mechanisms for FA detection, including 2-aza-Cope rearrangement, methylenehydrazine reaction, formimine formation, and other mechanisms. Furthermore, this review underscores the practical applications of these probes in real-world contexts, namely their incorporation into test strips, hydrogels, and membranes for environmental monitoring and food safety. Moreover, this review highlights future directions for developing intelligent detection systems that combine fluorescent probes with data processing algorithms and artificial intelligence technologies. By synthesizing the current knowledge in this area, this review aims to stimulate future research and advancements in FA detection technology, ultimately contributing to improved environmental management and public health protection.
期刊介绍:
Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.