Yilin Zheng, Haiquan Feng, Qingsong Han, Yonggang Wang, Juan Su
{"title":"椎动脉起始段狭窄治疗中不同植入深度对血流动力学的影响。","authors":"Yilin Zheng, Haiquan Feng, Qingsong Han, Yonggang Wang, Juan Su","doi":"10.1080/10255842.2025.2480269","DOIUrl":null,"url":null,"abstract":"<p><p>Stent implantation depth significantly influences the hemodynamics of the vertebral and subclavian arteries in treating vertebral artery stenosis. This study utilized computational fluid dynamics (CFD) to analyze key hemodynamic parameters in a vertebral artery model with a stent implanted at different depths. Results showed that excessive stent extension into the subclavian artery alters local blood flow, increasing the risk of thrombosis and plaque formation. An optimal implantation depth of 1-2 mm minimizes these risks. These findings provide a theoretical basis for optimizing stent placement, improving the efficacy and safety of interventional treatments for vertebral artery stenosis.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"841-854"},"PeriodicalIF":1.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The influence of different implantation depths on the hemodynamics in the treatment of stenosis in the starting segment of vertebral arteries.\",\"authors\":\"Yilin Zheng, Haiquan Feng, Qingsong Han, Yonggang Wang, Juan Su\",\"doi\":\"10.1080/10255842.2025.2480269\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Stent implantation depth significantly influences the hemodynamics of the vertebral and subclavian arteries in treating vertebral artery stenosis. This study utilized computational fluid dynamics (CFD) to analyze key hemodynamic parameters in a vertebral artery model with a stent implanted at different depths. Results showed that excessive stent extension into the subclavian artery alters local blood flow, increasing the risk of thrombosis and plaque formation. An optimal implantation depth of 1-2 mm minimizes these risks. These findings provide a theoretical basis for optimizing stent placement, improving the efficacy and safety of interventional treatments for vertebral artery stenosis.</p>\",\"PeriodicalId\":50640,\"journal\":{\"name\":\"Computer Methods in Biomechanics and Biomedical Engineering\",\"volume\":\" \",\"pages\":\"841-854\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computer Methods in Biomechanics and Biomedical Engineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1080/10255842.2025.2480269\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer Methods in Biomechanics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/10255842.2025.2480269","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
The influence of different implantation depths on the hemodynamics in the treatment of stenosis in the starting segment of vertebral arteries.
Stent implantation depth significantly influences the hemodynamics of the vertebral and subclavian arteries in treating vertebral artery stenosis. This study utilized computational fluid dynamics (CFD) to analyze key hemodynamic parameters in a vertebral artery model with a stent implanted at different depths. Results showed that excessive stent extension into the subclavian artery alters local blood flow, increasing the risk of thrombosis and plaque formation. An optimal implantation depth of 1-2 mm minimizes these risks. These findings provide a theoretical basis for optimizing stent placement, improving the efficacy and safety of interventional treatments for vertebral artery stenosis.
期刊介绍:
The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.