[婴儿配方奶粉中氯丙醇及相关物质的高灵敏度分析验证]。

IF 0.2 4区 农林科学 Q4 FOOD SCIENCE & TECHNOLOGY
Yudai Iwabe, Eisuke Toriumi, Mikihiko Yoshida, Kazushi Mizukoshi, Tomoji Igarashi
{"title":"[婴儿配方奶粉中氯丙醇及相关物质的高灵敏度分析验证]。","authors":"Yudai Iwabe, Eisuke Toriumi, Mikihiko Yoshida, Kazushi Mizukoshi, Tomoji Igarashi","doi":"10.3358/shokueishi.66.19","DOIUrl":null,"url":null,"abstract":"<p><p>Chloropropanols and related substances have received a great deal of attention in the world. Regulation values have already been established in the EU for infant formula. There are several validated analytical methods for these substances, such as the AOAC official method. However, no analytical official method has been established for infant formula in Japan. In this study, the AOAC official method was improved to a more versatile splitless injection method in order to make it feasible for many laboratories. The results of the validation data for the improved method with optimized injection conditions were as follows. The limit of quantification was 10 μg/kg, the recovery rate ranged from 81.6 to 114.5%, and the intermediate precision ranged from 1.6 to 7.6%. These results were adapt to AOAC and EU requirement and demonstrated the good validity of the improved method.</p>","PeriodicalId":54373,"journal":{"name":"Food Hygiene and Safety Science","volume":"66 1","pages":"19-24"},"PeriodicalIF":0.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Validation of High-Sensitivity Analysis for Chloropropanols and Related Substances in Infant Formula].\",\"authors\":\"Yudai Iwabe, Eisuke Toriumi, Mikihiko Yoshida, Kazushi Mizukoshi, Tomoji Igarashi\",\"doi\":\"10.3358/shokueishi.66.19\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Chloropropanols and related substances have received a great deal of attention in the world. Regulation values have already been established in the EU for infant formula. There are several validated analytical methods for these substances, such as the AOAC official method. However, no analytical official method has been established for infant formula in Japan. In this study, the AOAC official method was improved to a more versatile splitless injection method in order to make it feasible for many laboratories. The results of the validation data for the improved method with optimized injection conditions were as follows. The limit of quantification was 10 μg/kg, the recovery rate ranged from 81.6 to 114.5%, and the intermediate precision ranged from 1.6 to 7.6%. These results were adapt to AOAC and EU requirement and demonstrated the good validity of the improved method.</p>\",\"PeriodicalId\":54373,\"journal\":{\"name\":\"Food Hygiene and Safety Science\",\"volume\":\"66 1\",\"pages\":\"19-24\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Hygiene and Safety Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.3358/shokueishi.66.19\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Hygiene and Safety Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3358/shokueishi.66.19","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

氯丙醇及其相关物质在国际上受到了极大的关注。欧盟已经建立了婴儿配方奶粉的监管值。这些物质有几种经过验证的分析方法,如AOAC官方方法。然而,日本还没有为婴儿配方奶粉建立官方的分析方法。在本研究中,将AOAC官方方法改进为更通用的无分裂注射方法,以使其在许多实验室中可行。优化进样条件下改进方法的验证数据如下:定量限为10 μg/kg,加样回收率为81.6 ~ 114.5%,中间精密度为1.6 ~ 7.6%。结果符合AOAC和EU的要求,证明了改进方法的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Validation of High-Sensitivity Analysis for Chloropropanols and Related Substances in Infant Formula].

Chloropropanols and related substances have received a great deal of attention in the world. Regulation values have already been established in the EU for infant formula. There are several validated analytical methods for these substances, such as the AOAC official method. However, no analytical official method has been established for infant formula in Japan. In this study, the AOAC official method was improved to a more versatile splitless injection method in order to make it feasible for many laboratories. The results of the validation data for the improved method with optimized injection conditions were as follows. The limit of quantification was 10 μg/kg, the recovery rate ranged from 81.6 to 114.5%, and the intermediate precision ranged from 1.6 to 7.6%. These results were adapt to AOAC and EU requirement and demonstrated the good validity of the improved method.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Food Hygiene and Safety Science
Food Hygiene and Safety Science Medicine-Public Health, Environmental and Occupational Health
CiteScore
0.70
自引率
0.00%
发文量
28
审稿时长
18-36 weeks
期刊介绍: Information not localized
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信