Basiliximab治疗il -2相关炎症性疾病伴特应性皮炎。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-09-01 Epub Date: 2025-02-25 DOI:10.1111/pde.15913

Sarah L Becker, Liza Kenny, Alison Small

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引用次数: 0

摘要

对于对生物制剂无反应的严重特应性皮炎儿科患者的选择仍然有限。我们报告一例10岁男孩患有严重的顽固性特应性皮炎，伴发作性发热、关节痛和血清IL-2R升高，对巴希利昔单抗有反应。据我们所知，这是第一次报道使用basiliximab治疗儿童特应性皮炎。该病例强调了basiliximab作为治疗严重特应性皮炎病例的潜力，以及皮肤科精准医学的潜力。

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Basiliximab for IL-2-Associated Inflammatory Disorder With Atopic Dermatitis.

Options for pediatric patients with severe atopic dermatitis who do not respond to biologics remain limited. We report the case of a 10-year-old boy with severe, recalcitrant atopic dermatitis associated with episodic fever, joint pains, and elevated serum IL-2R, which responded to basiliximab. To our knowledge, this is the first reported use of basiliximab for atopic dermatitis in a pediatric patient. This case highlights the potential for basiliximab as a therapy for severe cases of atopic dermatitis and the potential for precision medicine in dermatology.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.