基于多目标粒子群算法的动态多叶准直器优化。

IF 1.4 3区 医学 Q3 INSTRUMENTS & INSTRUMENTATION
Journal of X-Ray Science and Technology Pub Date : 2025-01-01 Epub Date: 2024-12-26 DOI:10.1177/08953996241304986
Jun Lv, Liuli Chen, Zhiqiang Zhu, Pengcheng Long, Liqin Hu
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引用次数: 0

摘要

背景:动态多叶准直仪(dynamic multi-leaf colliator, DMLC)在x射线整形中起着至关重要的作用,可显著提高肿瘤放疗的精度、效率和质量。目的:对影响准直器性能的DMLC叶片端部结构进行优化,提高x射线的整形效果。方法:创新性地应用多目标粒子群优化(MOPSO)算法对DMLC参数进行优化,包括叶端半径、源叶距离、叶高、叶端与中心轴的切角等。主要的优化目标是最小化半影的宽度和方差,定义为80%和20%剂量的x射线在等心平面上的距离,这直接影响治疗精度。结果:在不同情况下,结构优化显著改善了半影的大小和均匀性,确保了更精确的辐射剂量。基于优化后的结构,设计了MLC的三维模型,并制作了实验样机进行了性能测试。结果表明,优化后的MLC具有较小的半影。结论:所提出的优化方法显著提高了放疗的精度,同时最大限度地减少了对健康组织的辐射暴露,是放疗技术的显著进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimization of dynamic multi-leaf collimator based on multi-objective particle swarm optimization algorithm.

Background: The dynamic multi-leaf collimator (DMLC) plays a crucial role in shaping X-rays, significantly enhancing the precision, efficiency, and quality of tumor radiotherapy.

Objective: To improve the shaping effect of X-rays by optimizing the end structure of the DMLC leaf, which significantly impacts the collimator's performance.

Methods: This study introduces the innovative application of the multi-objective particle swarm optimization (MOPSO) algorithm to optimize DMLC parameters, including leaf end radius, source-to-leaf distance, leaf height, and tangent angle between the leaf end and the central axis. The main optimization objectives are to minimize the width and variance of the penumbra, defined as the distance between the 80% and 20% dose of X-rays on the isocenter plane, which directly impacts treatment accuracy.

Results: Structural optimization across various scenarios showed significant improvements in the size and uniformity of the penumbra, ensuring a more precise radiation dose. Based on the optimized structure, a three-dimensional model of the MLC was designed and an experimental prototype was fabricated for performance testing. The results indicate that the optimized MLC exhibits a smaller penumbra.

Conclusion: The proposed optimization method significantly enhances the precision of radiotherapy while minimizing radiation exposure to healthy tissue, representing a notable advancement in radiotherapy technology.

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来源期刊
CiteScore
4.90
自引率
23.30%
发文量
150
审稿时长
3 months
期刊介绍: Research areas within the scope of the journal include: Interaction of x-rays with matter: x-ray phenomena, biological effects of radiation, radiation safety and optical constants X-ray sources: x-rays from synchrotrons, x-ray lasers, plasmas, and other sources, conventional or unconventional Optical elements: grazing incidence optics, multilayer mirrors, zone plates, gratings, other diffraction optics Optical instruments: interferometers, spectrometers, microscopes, telescopes, microprobes
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