巨Y染色体的快速动态进化

IF 45.8 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Science Pub Date : 2025-02-06

Takashi Akagi, Naoko Fujita, Kenta Shirasawa, Hiroyuki Tanaka, Kiyotaka Nagaki, Kanae Masuda, Ayano Horiuchi, Eriko Kuwada, Kanta Kawai, Riko Kunou, Koki Nakamura, Yoko Ikeda, Atsushi Toyoda, Takehiko Itoh, Koichiro Ushijima, Deborah Charlesworth

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引用次数: 0

摘要

一些植物有大量的性别连锁区域。为了验证关于它们进化的假设，我们对Silene latifolia的基因组进行了测序，其中巨大的异型性染色体于1923年首次被发现。人们早就知道，Y染色体主要由一个不与X染色体重组的男性特异性区域组成，该区域携带决定性别的基因和具有其他男性功能的基因。然而，只有在一个完整的Y染色体组合中，候选基因才能被实验验证，并确定它们的位置，并与抑制重组有关。我们描述了祖先染色体进化成当前的XY对时的基因组变化，测试了关于大型非重组区域进化的想法和创造当前重组模式的机制。

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Rapid and dynamic evolution of a giant Y chromosome in Silene latifolia

Some plants have massive sex-linked regions. To test hypotheses about their evolution, we sequenced the genome of Silene latifolia, in which giant heteromorphic sex chromosomes were first discovered in 1923. It has long been known that the Y chromosome consists mainly of a male-specific region that does not recombine with the X chromosome and carries the sex-determining genes and genes with other male functions. However, only with a whole Y chromosome assembly can candidate genes be validated experimentally and their locations determined and related to the suppression of recombination. We describe the genomic changes as the ancestral chromosome evolved into the current XY pair, testing ideas about the evolution of large nonrecombining regions and the mechanisms that created the present recombination pattern.

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来源期刊

Science 综合性期刊-综合性期刊

CiteScore

61.10

自引率

0.90%

发文量

审稿时长

2.1 months

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