2例中国后裔特应性皮炎患儿唇部黑色素斑。

IF 1.2 4区医学 Q3 DERMATOLOGY

Pediatric Dermatology Pub Date : 2025-07-01 Epub Date: 2025-01-29 DOI:10.1111/pde.15879

Apostolos Katsiaunis, Madalyn Petrillo, Sarah N Robinson

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引用次数: 0

摘要

我们报告了两名患有特应性皮炎（AD）的华裔儿童患者，他们在没有使用局部钙调磷酸酶抑制剂（TCI）的情况下出现了唇黑色斑。两例患者均表现为上、下朱唇多发色素沉着斑，peutz - jegers基因检查阴性。这些发现提示，唇黑色斑可能是儿童慢性湿疹性皮炎的一种皮肤表现，特别是那些亚洲血统的儿童。提高对这一现象的认识可能有助于临床医生做出治疗决定，避免不必要的基因检测，从而优化患者护理并降低成本。

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Labial Melanotic Macules in Two Pediatric Patients of Chinese Descent With Atopic Dermatitis.

We report two pediatric patients of Chinese descent with atopic dermatitis (AD) who developed labial melanotic macules in the absence of previous topical calcineurin inhibitor (TCI) usage. Both patients presented with multiple hyperpigmented macules on the upper and lower vermilion lips with a negative genetic workup for Peutz-Jeghers. These findings suggest labial melanotic macules may be a cutaneous manifestation of chronic eczematous dermatitis in pediatric patients, particularly those of Asian descent. Increased recognition of this phenomenon may help clinicians as they are making treatment decisions and avoid unnecessary genetic testing, thus optimizing patient care and reducing costs.

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来源期刊

Pediatric Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

6.70%

发文量

269

审稿时长

1 months

期刊介绍： Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.