EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Maria Bastos, Georges Bories, Pier Sandro Cocconcelli, Noel Dierik, Jürgen Gropp, Fernando Ramos, Jaume Galobart, Orsolya Holczknecht, Paola Manini, Jordi Ortuño, Alberto Navarro Villa, Fabiola Pizzo, Anna Dioni, Maria Vittoria Vettori
{"title":"修改由角黄素组成的饲料添加剂的授权条款,用于育肥鸡、用于育肥的小型家禽品种、产蛋家禽和饲养的产蛋家禽、观赏鱼类和观赏鸟类以及观赏种鸡,以包括用脂性耶罗氏菌CBS 146148(帝斯曼营养产品有限公司)生产的角黄素。","authors":"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Maria Bastos, Georges Bories, Pier Sandro Cocconcelli, Noel Dierik, Jürgen Gropp, Fernando Ramos, Jaume Galobart, Orsolya Holczknecht, Paola Manini, Jordi Ortuño, Alberto Navarro Villa, Fabiola Pizzo, Anna Dioni, Maria Vittoria Vettori","doi":"10.2903/j.efsa.2025.9134","DOIUrl":null,"url":null,"abstract":"<p>Following a request from the European Commission, the European Food Safety Authority was asked to deliver a scientific opinion on the proposed modification of the terms of the authorisation of canthaxanthin, regarding the addition of a new production route, by the yeast <i>Yarrowia lipolytica</i> CBS 146148. The additive is already authorised as sensory feed additive for use in feed for chickens for fattening, minor poultry species for fattening, laying poultry, poultry reared for laying, ornamental fish, ornamental birds and ornamental breeder hens. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that canthaxanthin produced with <i>Yarrowia lipolytica</i> CBS 146148 is considered safe for the target species, the consumer and the environment under the current authorised conditions of use. Canthaxanthin is not an irritant to skin or eyes and it is unlikely to be a skin sensitiser. No conclusion can be reached on the respiratory sensitisation of canthaxanthin. In the absence of data, no conclusions on the safety for the user can be reached for any preparation produced with canthaxanthin. Canthaxanthin produced by fermentation with <i>Y. lipolytica</i> CBS 146148 is efficacious as a colouring agent in feed for chickens for fattening and minor poultry species for fattening, laying poultry and poultry reared for laying, ornamental fish and ornamental birds.</p>","PeriodicalId":11657,"journal":{"name":"EFSA Journal","volume":"23 1","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733588/pdf/","citationCount":"0","resultStr":"{\"title\":\"Modification of the terms of authorisation of the feed additive consisting of canthaxanthin for chickens for fattening, minor poultry species for fattening, laying poultry and poultry reared for laying, ornamental fish and ornamental birds and ornamental breeder hens to include canthaxanthin produced with Yarrowia lipolytica CBS 146148 (DSM Nutritional Products Ltd.)\",\"authors\":\"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López-Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto-Maradona, Ilen Röhe, Katerina Theodoridou, Maria Bastos, Georges Bories, Pier Sandro Cocconcelli, Noel Dierik, Jürgen Gropp, Fernando Ramos, Jaume Galobart, Orsolya Holczknecht, Paola Manini, Jordi Ortuño, Alberto Navarro Villa, Fabiola Pizzo, Anna Dioni, Maria Vittoria Vettori\",\"doi\":\"10.2903/j.efsa.2025.9134\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Following a request from the European Commission, the European Food Safety Authority was asked to deliver a scientific opinion on the proposed modification of the terms of the authorisation of canthaxanthin, regarding the addition of a new production route, by the yeast <i>Yarrowia lipolytica</i> CBS 146148. The additive is already authorised as sensory feed additive for use in feed for chickens for fattening, minor poultry species for fattening, laying poultry, poultry reared for laying, ornamental fish, ornamental birds and ornamental breeder hens. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that canthaxanthin produced with <i>Yarrowia lipolytica</i> CBS 146148 is considered safe for the target species, the consumer and the environment under the current authorised conditions of use. Canthaxanthin is not an irritant to skin or eyes and it is unlikely to be a skin sensitiser. No conclusion can be reached on the respiratory sensitisation of canthaxanthin. In the absence of data, no conclusions on the safety for the user can be reached for any preparation produced with canthaxanthin. Canthaxanthin produced by fermentation with <i>Y. lipolytica</i> CBS 146148 is efficacious as a colouring agent in feed for chickens for fattening and minor poultry species for fattening, laying poultry and poultry reared for laying, ornamental fish and ornamental birds.</p>\",\"PeriodicalId\":11657,\"journal\":{\"name\":\"EFSA Journal\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2025-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733588/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"EFSA Journal\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9134\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"EFSA Journal","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025.9134","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
Modification of the terms of authorisation of the feed additive consisting of canthaxanthin for chickens for fattening, minor poultry species for fattening, laying poultry and poultry reared for laying, ornamental fish and ornamental birds and ornamental breeder hens to include canthaxanthin produced with Yarrowia lipolytica CBS 146148 (DSM Nutritional Products Ltd.)
Following a request from the European Commission, the European Food Safety Authority was asked to deliver a scientific opinion on the proposed modification of the terms of the authorisation of canthaxanthin, regarding the addition of a new production route, by the yeast Yarrowia lipolytica CBS 146148. The additive is already authorised as sensory feed additive for use in feed for chickens for fattening, minor poultry species for fattening, laying poultry, poultry reared for laying, ornamental fish, ornamental birds and ornamental breeder hens. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that canthaxanthin produced with Yarrowia lipolytica CBS 146148 is considered safe for the target species, the consumer and the environment under the current authorised conditions of use. Canthaxanthin is not an irritant to skin or eyes and it is unlikely to be a skin sensitiser. No conclusion can be reached on the respiratory sensitisation of canthaxanthin. In the absence of data, no conclusions on the safety for the user can be reached for any preparation produced with canthaxanthin. Canthaxanthin produced by fermentation with Y. lipolytica CBS 146148 is efficacious as a colouring agent in feed for chickens for fattening and minor poultry species for fattening, laying poultry and poultry reared for laying, ornamental fish and ornamental birds.
期刊介绍:
The EFSA Journal covers methods of risk assessment, reports on data collected, and risk assessments in the individual areas of plant health, plant protection products and their residues, genetically modified organisms, additives and products or substances used in animal feed, animal health and welfare, biological hazards including BSE/TSE, contaminants in the food chain, food contact materials, enzymes, flavourings and processing aids, food additives and nutrient sources added to food, dietetic products, nutrition and allergies.