{"title":"通过再激活先天免疫疗法恢复衰老相关组织的稳态。","authors":"","doi":"10.1038/s43587-024-00782-1","DOIUrl":null,"url":null,"abstract":"A chimeric peptide designed to recruit immune cells has been shown to enhance the ‘coupling’ between senescent cells and natural killer cells to promote immune clearance of senescent cells for restoration of tissue homeostasis in liver fibrosis, lung injury, cancer and even natural aging in mice.","PeriodicalId":94150,"journal":{"name":"Nature aging","volume":"5 1","pages":"17-18"},"PeriodicalIF":17.0000,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Restoring aging-related tissue homeostasis via reactivated innate immunotherapy\",\"authors\":\"\",\"doi\":\"10.1038/s43587-024-00782-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A chimeric peptide designed to recruit immune cells has been shown to enhance the ‘coupling’ between senescent cells and natural killer cells to promote immune clearance of senescent cells for restoration of tissue homeostasis in liver fibrosis, lung injury, cancer and even natural aging in mice.\",\"PeriodicalId\":94150,\"journal\":{\"name\":\"Nature aging\",\"volume\":\"5 1\",\"pages\":\"17-18\"},\"PeriodicalIF\":17.0000,\"publicationDate\":\"2025-01-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature aging\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.nature.com/articles/s43587-024-00782-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature aging","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s43587-024-00782-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
Restoring aging-related tissue homeostasis via reactivated innate immunotherapy
A chimeric peptide designed to recruit immune cells has been shown to enhance the ‘coupling’ between senescent cells and natural killer cells to promote immune clearance of senescent cells for restoration of tissue homeostasis in liver fibrosis, lung injury, cancer and even natural aging in mice.
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