在未受影响的强迫症一级亲属中使用爱荷华赌博测试的决策：与健康对照和强迫症患者的比较。

IF 2 4区心理学 Q2 PSYCHOLOGY

Journal of Neuropsychology Pub Date : 2024-12-17 DOI:10.1111/jnp.12407

Keitaro Murayama, Hirofumi Tomiyama, Aikana Ohono, Kenta Kato, Akira Matsuo, Mingi Kang, Tomohiro Nakao

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引用次数: 0

摘要

决策被认为是强迫症（OCD）的一种内表型候选者。然而，很少有研究调查模糊决策是否是强迫症的一种内表型。本研究旨在通过爱荷华赌博任务（IGT）评估强迫症患者和未受影响的一级亲属（UFDR）在模糊情况下的决策。在使用IGT的决策方面，比较了47名非药物治疗、非合并症的强迫症患者、30名UFDR患者和47名健康对照（HC）。强迫性症状与IGT表现之间的相关性也被调查。OCD和UFDR患者在IGT上的表现比HC患者差。强迫性症状与IGT表现之间没有相关性。模糊性下的决策缺陷可能是强迫症的一种特征和内表型候选者。

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Decision-making using the Iowa gambling test in unaffected first-degree relatives of obsessive-compulsive disorder: Comparison with healthy controls and patients with obsessive-compulsive disorder.

Decision-making has been suggested as an endophenotype candidate for obsessive-compulsive disorder (OCD). However, few studies have examined whether decision-making under ambiguity is an endophenotype of OCD. This study aimed to investigate decision-making under ambiguity, as assessed by the Iowa Gambling Task (IGT), in patients with OCD and unaffected first-degree relatives (UFDR). Forty-seven non-medicated, non-co-morbid patients with OCD, 30 UFDR, and 47 healthy controls (HC) were compared in terms of decision-making using the IGT. The correlation between obsessive-compulsive symptoms and IGT performance was also investigated. Patients with OCD and UFDR performed worse than HC on the IGT. No correlation was found between obsessive-compulsive symptoms and IGT performance. A deficit in decision-making under ambiguity may be a trait and an endophenotype candidate for OCD.

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来源期刊

Journal of Neuropsychology 医学-心理学

CiteScore

4.50

自引率

4.50%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Neuropsychology publishes original contributions to scientific knowledge in neuropsychology including: • clinical and research studies with neurological, psychiatric and psychological patient populations in all age groups • behavioural or pharmacological treatment regimes • cognitive experimentation and neuroimaging • multidisciplinary approach embracing areas such as developmental psychology, neurology, psychiatry, physiology, endocrinology, pharmacology and imaging science The following types of paper are invited: • papers reporting original empirical investigations • theoretical papers; provided that these are sufficiently related to empirical data • review articles, which need not be exhaustive, but which should give an interpretation of the state of research in a given field and, where appropriate, identify its clinical implications • brief reports and comments • case reports • fast-track papers (included in the issue following acceptation) reaction and rebuttals (short reactions to publications in JNP followed by an invited rebuttal of the original authors) • special issues.