{"title":"基于金属有机框架修饰金电极上的分子印迹聚合物涂层开发电化学 3-MCPD 传感器","authors":"Vasfiye Hazal Özyurt , Göksu Can , Ülkü Anık","doi":"10.1016/j.jfca.2024.107004","DOIUrl":null,"url":null,"abstract":"<div><div>3-Chloropropane-1,2-diol (3-MCPD) is formed during the food processing and defined as a potential carcinogen. For this reason practical, effective and economical detection of this substance is crucial. In this work, Fe-MIL-88-metal organic framework (MOF) included electrochemical molecularly imprinted polymer (MIP) based sensor was designed for 3-MCPD detection. Gold screen printed electrodes (AuSPE) were modified with MOF structure and then a MIP layer was formed on the electrode surface via electropolymerization where aniline was used as a monomer and 3-MCPD as a template molecule. In order to improve the response of the prepared sensor, various experimental parameters such as MOF amount, MIP layer thickness, template molecule: monomer ratio, extraction time and rebinding time were optimized. Then, as an analytical characteristic parameter, linear ranges were detected for 3-MCPD in the range of 0.05 μM to 0.5 μM with a limit of detection (LOD) value of 0.43 μM as well as in the range of 0.05 and 0.5 μM with LOD value of 0.01 μM. The specificity of the developed electrochemical sensor was investigated in the presence of interferent reagents and then developed sensor was adapted for 3-MCPD determination in vegetable oil and soy sauce. Lastly the real sample analysis was also validated with gas chromatograpy-mass spectrometry technique which is accepted as gold standard method for 3-MCPD analysis.</div></div>","PeriodicalId":15867,"journal":{"name":"Journal of Food Composition and Analysis","volume":"138 ","pages":"Article 107004"},"PeriodicalIF":4.0000,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of electrochemical 3-MCPD sensor based on molecularly imprinted polymer coating on metal organic framework modified gold electrode\",\"authors\":\"Vasfiye Hazal Özyurt , Göksu Can , Ülkü Anık\",\"doi\":\"10.1016/j.jfca.2024.107004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>3-Chloropropane-1,2-diol (3-MCPD) is formed during the food processing and defined as a potential carcinogen. For this reason practical, effective and economical detection of this substance is crucial. In this work, Fe-MIL-88-metal organic framework (MOF) included electrochemical molecularly imprinted polymer (MIP) based sensor was designed for 3-MCPD detection. Gold screen printed electrodes (AuSPE) were modified with MOF structure and then a MIP layer was formed on the electrode surface via electropolymerization where aniline was used as a monomer and 3-MCPD as a template molecule. In order to improve the response of the prepared sensor, various experimental parameters such as MOF amount, MIP layer thickness, template molecule: monomer ratio, extraction time and rebinding time were optimized. Then, as an analytical characteristic parameter, linear ranges were detected for 3-MCPD in the range of 0.05 μM to 0.5 μM with a limit of detection (LOD) value of 0.43 μM as well as in the range of 0.05 and 0.5 μM with LOD value of 0.01 μM. The specificity of the developed electrochemical sensor was investigated in the presence of interferent reagents and then developed sensor was adapted for 3-MCPD determination in vegetable oil and soy sauce. Lastly the real sample analysis was also validated with gas chromatograpy-mass spectrometry technique which is accepted as gold standard method for 3-MCPD analysis.</div></div>\",\"PeriodicalId\":15867,\"journal\":{\"name\":\"Journal of Food Composition and Analysis\",\"volume\":\"138 \",\"pages\":\"Article 107004\"},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Food Composition and Analysis\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S088915752401038X\",\"RegionNum\":2,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Food Composition and Analysis","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S088915752401038X","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Development of electrochemical 3-MCPD sensor based on molecularly imprinted polymer coating on metal organic framework modified gold electrode
3-Chloropropane-1,2-diol (3-MCPD) is formed during the food processing and defined as a potential carcinogen. For this reason practical, effective and economical detection of this substance is crucial. In this work, Fe-MIL-88-metal organic framework (MOF) included electrochemical molecularly imprinted polymer (MIP) based sensor was designed for 3-MCPD detection. Gold screen printed electrodes (AuSPE) were modified with MOF structure and then a MIP layer was formed on the electrode surface via electropolymerization where aniline was used as a monomer and 3-MCPD as a template molecule. In order to improve the response of the prepared sensor, various experimental parameters such as MOF amount, MIP layer thickness, template molecule: monomer ratio, extraction time and rebinding time were optimized. Then, as an analytical characteristic parameter, linear ranges were detected for 3-MCPD in the range of 0.05 μM to 0.5 μM with a limit of detection (LOD) value of 0.43 μM as well as in the range of 0.05 and 0.5 μM with LOD value of 0.01 μM. The specificity of the developed electrochemical sensor was investigated in the presence of interferent reagents and then developed sensor was adapted for 3-MCPD determination in vegetable oil and soy sauce. Lastly the real sample analysis was also validated with gas chromatograpy-mass spectrometry technique which is accepted as gold standard method for 3-MCPD analysis.
期刊介绍:
The Journal of Food Composition and Analysis publishes manuscripts on scientific aspects of data on the chemical composition of human foods, with particular emphasis on actual data on composition of foods; analytical methods; studies on the manipulation, storage, distribution and use of food composition data; and studies on the statistics, use and distribution of such data and data systems. The Journal''s basis is nutrient composition, with increasing emphasis on bioactive non-nutrient and anti-nutrient components. Papers must provide sufficient description of the food samples, analytical methods, quality control procedures and statistical treatments of the data to permit the end users of the food composition data to evaluate the appropriateness of such data in their projects.
The Journal does not publish papers on: microbiological compounds; sensory quality; aromatics/volatiles in food and wine; essential oils; organoleptic characteristics of food; physical properties; or clinical papers and pharmacology-related papers.