2024 年埃塞俄比亚东部 Hiwot Fana 综合专科医院食疗中心收治的五岁以下儿童严重急性营养不良的恢复时间及其预测因素:半参数模型。

IF 4 2区 农林科学 Q2 NUTRITION & DIETETICS
Frontiers in Nutrition Pub Date : 2024-11-05 eCollection Date: 2024-01-01 DOI:10.3389/fnut.2024.1450496
Fentahun Meseret, Mulualem Keneni, Ayichew Alemu, Diribsa Tizazu, Tesfaye Asfaw Alemayehu, Yalew Mossie, Tilahun Teshager, Fenta Wondimneh
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引用次数: 0

摘要

背景:对于因严重急性营养不良(SAM)而入住食疗中心的五岁以下儿童而言,早期康复是衡量优质护理的一项绩效指标。尽管现有干预措施可解决此类营养问题,但有关埃塞俄比亚严重急性营养不良儿童的康复时间及其预测因素的信息却很有限,尤其是在研究环境中:本研究旨在评估 2019 年 9 月 1 日至 2024 年 3 月 1 日期间在埃塞俄比亚东部 Hiwot Fana 综合专科医院(HFCSH)治疗喂养中心(TFC)住院的 6-59 个月儿童从严重急性营养不良中恢复的时间及其预测因素:在HFCSH的治疗喂养中心对随机抽取的349名正在接受治疗喂养的严重急性营养不良患者进行了一项回顾性队列研究。研究使用数据摘要工具收集数据,然后将数据存储在 Epi-data 4.6 版和 STATA 17.0 版统计软件中。本研究采用描述性统计、Kaplan-Meier(KM)图、中位数生存时间、对数秩检验和 Cox 比例危险回归模型来报告研究结果。在进行 Cox 比例危险度回归后,对模型的拟合度和假设进行了检验。最后,使用多变量 Cox 比例危险度模型评估了自变量与康复时间(天数)之间的关系,并对 p 值的变量进行了结果分析:严重急性营养不良患者的中位康复生存时间为17天[95%置信区间(CI):16-18]。发病密度恢复率为每 100 个观察日 5.7(95%CI,4.9-6.6)。影响康复时间的因素包括居住在农村地区[调整后危险比(AHR)=2.072;95%CI=1.336-3.215]、根据年龄接种疫苗(AHR=1.848;95%CI=1.162-2.939)和未使用镇痛剂(AHR=0.685;95%CI=0.472-0.995):结论:本研究发现中位康复存活时间是最佳的。结论:本研究发现,康复的中位存活时间是最理想的。居住地、儿童的疫苗接种情况和镇痛剂的使用是决定性因素。作为治疗方案的一部分,关注疫苗接种覆盖率、发烧控制和疼痛控制有助于缩短住院时间,提高埃塞俄比亚五岁以下严重营养不良儿童的康复率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recovery time and its predictors of severe acute malnutrition among under five children admitted at the therapeutic feeding center of Hiwot Fana comprehensive specialized hospital, eastern Ethiopia, 2024: a semi-parametric model.

Background: Early recovery is a performance indicator of quality care for children under five admitted due to severe acute malnutrition (SAM) at therapeutic feeding centers. Despite the available interventions to tackle such nutritional problems, there is limited information on the time to recovery and its predictors among children with severe acute malnutrition in Ethiopia, more particularly in the study setting.

Objective: The study aimed to assess the time to recovery from severe acute malnutrition and its predictors among children aged 6-59 months admitted to the therapeutic feeding center (TFC) of Hiwot Fana Comprehensive Specialized Hospital (HFCSH), eastern Ethiopia, from 1st September 2019 to 1st March 012024.

Methods: A retrospective cohort study was conducted at the therapeutic feeding center of HFCSH among a randomly selected sample of 349 patients with severe acute malnutrition who were undergoing therapeutic feeding. Data were collected using a data abstraction tool and then stored in Epi-data version 4.6 and STATA version 17.0 statistical software. Descriptive statistics, Kaplan-Meier (KM) plots, median survival times, the log-rank test, and the Cox proportional hazards regression model were used to report the findings of this study. After performing the Cox proportional hazards regression, the model goodness of fit and assumptions were checked. Finally, the association between independent variables and the time to recovery in days was assessed using the multivariable Cox proportional hazards model, and the variables with a p-value <0.05 were considered statistically significant.

Results: The median survival time to recovery among the patients with severe acute malnutrition was 17 days [95% confidence interval (CI): 16-18]. The incidence density recovery rate was 5.7 (95%CI, 4.9-6.6) per 100 person-days of observation. Factors that affected the time to recovery included residing in rural areas [adjusted hazard ratio (AHR) = 2.072; 95%CI = 1.336-3.215], being vaccinated according to age (AHR = 1.848; 95%CI = 1.162-2.939), and lack of analgesic administration (AHR = 0.685; 95%CI = 0.472-0.995).

Conclusion: The median survival time to recovery in this study was found to be optimal. Residency, vaccination status of the child, and analgesic administration were the determinant factors. Paying attention to vaccination coverage, fever management, and pain management as part of the protocol helps reduce the length of hospital stay by facilitating recovery rates among severely malnourished children under five in Ethiopia.

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来源期刊
Frontiers in Nutrition
Frontiers in Nutrition Agricultural and Biological Sciences-Food Science
CiteScore
5.20
自引率
8.00%
发文量
2891
审稿时长
12 weeks
期刊介绍: No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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