通过掺铽碳点和纳米铜簇的 AIE 和 FRET 对喹诺酮类药物进行荧光检测

IF 8.5 1区 农林科学 Q1 CHEMISTRY, APPLIED
Ramadan Ali , Reem Alshaman , Abdullah S. Albalawi , Osama M. Alsharif , Osama A. Hakami , Hamzah Hussain Alharthi , Faisal F. Jumah , Abdulrhman M. Al-Qarni , Naif S. Albalawi , Meshari Saud Alashjaee , Faisal S. Aljohani , Abdulaziz M. Alghuzawi , Muath H. Al-Atwi , Abdullah H. Alharbi , Mohamed M. El-Wekil
{"title":"通过掺铽碳点和纳米铜簇的 AIE 和 FRET 对喹诺酮类药物进行荧光检测","authors":"Ramadan Ali ,&nbsp;Reem Alshaman ,&nbsp;Abdullah S. Albalawi ,&nbsp;Osama M. Alsharif ,&nbsp;Osama A. Hakami ,&nbsp;Hamzah Hussain Alharthi ,&nbsp;Faisal F. Jumah ,&nbsp;Abdulrhman M. Al-Qarni ,&nbsp;Naif S. Albalawi ,&nbsp;Meshari Saud Alashjaee ,&nbsp;Faisal S. Aljohani ,&nbsp;Abdulaziz M. Alghuzawi ,&nbsp;Muath H. Al-Atwi ,&nbsp;Abdullah H. Alharbi ,&nbsp;Mohamed M. El-Wekil","doi":"10.1016/j.foodchem.2024.142076","DOIUrl":null,"url":null,"abstract":"<div><div>Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), combined with α-lipoic acid-functionalized copper nanoclusters (LA@CuNCs), were proposed for the ratiometric detection of quinolone (QA) antibiotics. In this system, Tb@N-CDs facilitate the aggregation of LA@CuNCs, enhancing its fluorescence emission at 670 nm via aggregation-induced emission enhancement (AIEE). Meanwhile, the fluorescence emission of Tb@N-CDs at 460 nm diminishes due to Förster resonance energy transfer (FRET). Upon the introduction of QA, the binding between Tb<sup>3+</sup> ions and N-CDs weakens, disrupting both AIEE and FRET processes. This disruption results in a reduction in fluorescence emission at 670 nm and a concurrent increase at 460 nm. The fluorescence response ratio (F<sub>460</sub>/F<sub>670</sub>) increases with higher concentrations of ciprofloxacin (CFX), demonstrating a linear range from 0.008 to 120 μmol L<sup>−1</sup> and LOD of 1.6 nmol L<sup>−1</sup>. The method successfully detected CFX in milk and urine samples, achieving recoveries between 97.7 % and 103.8 %, RSD of less than 3.79 %.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"465 ","pages":"Article 142076"},"PeriodicalIF":8.5000,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fluorometric detection of quinolones via AIE and FRET with terbium-doped carbon dots and copper nanoclusters\",\"authors\":\"Ramadan Ali ,&nbsp;Reem Alshaman ,&nbsp;Abdullah S. Albalawi ,&nbsp;Osama M. Alsharif ,&nbsp;Osama A. Hakami ,&nbsp;Hamzah Hussain Alharthi ,&nbsp;Faisal F. Jumah ,&nbsp;Abdulrhman M. Al-Qarni ,&nbsp;Naif S. Albalawi ,&nbsp;Meshari Saud Alashjaee ,&nbsp;Faisal S. Aljohani ,&nbsp;Abdulaziz M. Alghuzawi ,&nbsp;Muath H. Al-Atwi ,&nbsp;Abdullah H. Alharbi ,&nbsp;Mohamed M. El-Wekil\",\"doi\":\"10.1016/j.foodchem.2024.142076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), combined with α-lipoic acid-functionalized copper nanoclusters (LA@CuNCs), were proposed for the ratiometric detection of quinolone (QA) antibiotics. In this system, Tb@N-CDs facilitate the aggregation of LA@CuNCs, enhancing its fluorescence emission at 670 nm via aggregation-induced emission enhancement (AIEE). Meanwhile, the fluorescence emission of Tb@N-CDs at 460 nm diminishes due to Förster resonance energy transfer (FRET). Upon the introduction of QA, the binding between Tb<sup>3+</sup> ions and N-CDs weakens, disrupting both AIEE and FRET processes. This disruption results in a reduction in fluorescence emission at 670 nm and a concurrent increase at 460 nm. The fluorescence response ratio (F<sub>460</sub>/F<sub>670</sub>) increases with higher concentrations of ciprofloxacin (CFX), demonstrating a linear range from 0.008 to 120 μmol L<sup>−1</sup> and LOD of 1.6 nmol L<sup>−1</sup>. The method successfully detected CFX in milk and urine samples, achieving recoveries between 97.7 % and 103.8 %, RSD of less than 3.79 %.</div></div>\",\"PeriodicalId\":318,\"journal\":{\"name\":\"Food Chemistry\",\"volume\":\"465 \",\"pages\":\"Article 142076\"},\"PeriodicalIF\":8.5000,\"publicationDate\":\"2024-11-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Chemistry\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0308814624037269\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0308814624037269","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0

摘要

研究人员提出了铽和氮共掺杂碳点(Tb@N-CDs)与α-硫辛酸功能化纳米铜簇(LA@CuNCs)结合用于喹诺酮类抗生素(QA)的比率检测。在该系统中,Tb@N-CDs 可促进 LA@CuNCs 的聚集,通过聚集诱导发射增强(AIEE)提高其在 670 纳米波长处的荧光发射。同时,由于佛斯特共振能量转移(FRET),Tb@N-CDs 在 460 纳米波长处的荧光发射减弱。引入 QA 后,Tb3+ 离子与 N-CD 之间的结合减弱,从而破坏了 AIEE 和 FRET 过程。这种破坏导致 670 纳米波长处的荧光发射减少,同时 460 纳米波长处的荧光发射增加。荧光响应比(F460/F670)随着环丙沙星(CFX)浓度的增加而增加,线性范围为 0.008 至 120 μmol L-1,最低检测限为 1.6 nmol L-1。该方法成功检测了牛奶和尿液样品中的CFX,回收率在97.7%和103.8%之间,RSD小于3.79%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fluorometric detection of quinolones via AIE and FRET with terbium-doped carbon dots and copper nanoclusters
Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), combined with α-lipoic acid-functionalized copper nanoclusters (LA@CuNCs), were proposed for the ratiometric detection of quinolone (QA) antibiotics. In this system, Tb@N-CDs facilitate the aggregation of LA@CuNCs, enhancing its fluorescence emission at 670 nm via aggregation-induced emission enhancement (AIEE). Meanwhile, the fluorescence emission of Tb@N-CDs at 460 nm diminishes due to Förster resonance energy transfer (FRET). Upon the introduction of QA, the binding between Tb3+ ions and N-CDs weakens, disrupting both AIEE and FRET processes. This disruption results in a reduction in fluorescence emission at 670 nm and a concurrent increase at 460 nm. The fluorescence response ratio (F460/F670) increases with higher concentrations of ciprofloxacin (CFX), demonstrating a linear range from 0.008 to 120 μmol L−1 and LOD of 1.6 nmol L−1. The method successfully detected CFX in milk and urine samples, achieving recoveries between 97.7 % and 103.8 %, RSD of less than 3.79 %.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Food Chemistry
Food Chemistry 工程技术-食品科技
CiteScore
16.30
自引率
10.20%
发文量
3130
审稿时长
122 days
期刊介绍: Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信